Regulation of Glycogenolysis in Anaerobic Skeletal Muscle
type: CreativeWork
description: Functional compartmentation of anaerobic metabolism was demonstrated in intact tissue. Force-independent ATP utilization, primarily the Ca 2+ pump of the sarcoplasmic reticulum, preferentially uses ATP derived from glycogenolysis. ATP produced by creatine kinase is used mostly by force-dependent ATP consuming processes, primarily the actomyosin-ATPase. Although prior evidence of sub-cytosolic metabolic compartmentation exists, the majority of these studies are not in intact cells or tissues. The demonstration here of functional compartmentation of ATP production for specific ATPases shows that metabolism needs to be considered with this in mind.
abstract: Functional compartmentation of anaerobic metabolism was demonstrated in intact tissue. Force-independent ATP utilization, primarily the Ca 2+ pump of the sarcoplasmic reticulum, preferentially uses ATP derived from glycogenolysis. ATP produced by creatine kinase is used mostly by force-dependent ATP consuming processes, primarily the actomyosin-ATPase. Although prior evidence of sub-cytosolic metabolic compartmentation exists, the majority of these studies are not in intact cells or tissues. The demonstration here of functional compartmentation of ATP production for specific ATPases shows that metabolism needs to be considered with this in mind.
author: Hsu, Alexander Chong-Koang
language: eng
keywords: Biology, Animal Physiology
date published: 2015-09-25T22:46:02Z
date modified: 2026-07-22T22:26:25Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/85423