{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/84992"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/84992","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Testosterone, Lycopene Isomers, and Prostate Cancer","abstract":"The objective of the final study was to determine the influence of purified lycopene, tomato powder, and 20% diet restriction on N-methyl-N-nitrosourea (NMU)-testosterone-induced prostate cancer in rats. Survival was analyzed to include only rats that died with adenocarcinomas of the accessory sex glands. Only tomato powder-fed (RR = 0.570; P = 0.009) rats experienced significantly increased survival as compared to placebo beadlet-fed control rats. No significant influences of lycopene beadlet feeding or diet restriction as well as no interactions were noted for accessory sex gland-specific survival. We conclude that tomato powder may contain compounds, in addition to lycopene, which favorably modulate prostate carcinogenesis.","abstract_html":"The objective of the final study was to determine the influence of purified lycopene, tomato powder, and 20% diet restriction on N-methyl-N-nitrosourea (NMU)-testosterone-induced prostate cancer in rats. Survival was analyzed to include only rats that died with adenocarcinomas of the accessory sex glands. Only tomato powder-fed (RR = 0.570; P = 0.009) rats experienced significantly increased survival as compared to placebo beadlet-fed control rats. No significant influences of lycopene beadlet feeding or diet restriction as well as no interactions were noted for accessory sex gland-specific survival. We conclude that tomato powder may contain compounds, in addition to lycopene, which favorably modulate prostate carcinogenesis.","abstract_has_math":false,"creators":["Boileau, Thomas William-Maxwell"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Nutritional Sciences","degree_department":null,"school":null,"contributors":["John W. Erdman, Jr."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T22:31:14Z","date_published":"2015-09-25T22:31:14Z","updated_at":"2026-07-22T22:26:24Z","subjects":["Health Sciences, Oncology"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI9996618"],"render_values":[{"text":"(MiAaPQ)AAI9996618","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/84992","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["John W. 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Survival was analyzed to include only rats that died with adenocarcinomas of the accessory sex glands. Only tomato powder-fed (RR = 0.570; P = 0.009) rats experienced significantly increased survival as compared to placebo beadlet-fed control rats. No significant influences of lycopene beadlet feeding or diet restriction as well as no interactions were noted for accessory sex gland-specific survival. We conclude that tomato powder may contain compounds, in addition to lycopene, which favorably modulate prostate carcinogenesis.","Made available in DSpace on 2015-09-25T22:31:14Z (GMT). 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No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 9996618.pdf: 3974938 bytes, checksum: 6dbd050a6baf7c28c278a9e012171cde (MD5) Previous issue date: 2001","Embargo set by: Seth Robbins for item 86273 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","152 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2001."],"dc:identifier":["http://hdl.handle.net/2142/84992","(MiAaPQ)AAI9996618"],"dc:language":["eng"],"dc:subject":["Health Sciences, Oncology"],"dc:title":["Testosterone, Lycopene Isomers, and Prostate Cancer"],"dc:type":["text"],"thesis:degree_discipline":["Nutritional Sciences"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:24Z"}