{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/84979"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/84979","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Metabolic Responses During Recovery From Prolonged Exercise: Role of Nutrition and Hormones","abstract":"The second specific aim of this research was to investigate the regulation of insulin-like growth factor binding protein-1 production following exercise. Prolonged exercise increased plasma and hepatic levels of IGFBP-1. Neither plasma insulin and glucose levels, nor meal composition altered IGFBP-1 production following exercise. Conversely, adaptation to treadmill running markedly suppressed IGFBP-1 production, suggesting a connection between exercise stress and IGFBP-1. Further, plasma corticosterone correlated to plasma IGFBP-1 in untrained and treadmill-adapted animals following exercise. However, pre-treatment with drugs that block corticosterone synthesis and bioactivity did not prevent IGFBP-1 from rising following exercise. These results demonstrate that upregulation of IGFBP-1 following exercise is corticosteroid-independent. Further research is needed to determine the chemical factor(s) inducing IGFBP-1 production following exercise.","abstract_html":"The second specific aim of this research was to investigate the regulation of insulin-like growth factor binding protein-1 production following exercise. Prolonged exercise increased plasma and hepatic levels of IGFBP-1. Neither plasma insulin and glucose levels, nor meal composition altered IGFBP-1 production following exercise. Conversely, adaptation to treadmill running markedly suppressed IGFBP-1 production, suggesting a connection between exercise stress and IGFBP-1. Further, plasma corticosterone correlated to plasma IGFBP-1 in untrained and treadmill-adapted animals following exercise. However, pre-treatment with drugs that block corticosterone synthesis and bioactivity did not prevent IGFBP-1 from rising following exercise. These results demonstrate that upregulation of IGFBP-1 following exercise is corticosteroid-independent. Further research is needed to determine the chemical factor(s) inducing IGFBP-1 production following exercise.","abstract_has_math":false,"creators":["Gautsch, Tracy Anne"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Nutritional Sciences","degree_department":null,"school":null,"contributors":["Layman, Donald K."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T22:31:11Z","date_published":"2015-09-25T22:31:11Z","updated_at":"2026-07-22T22:26:24Z","subjects":["Health Sciences, Rehabilitation and Therapy"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI9904462"],"render_values":[{"text":"(MiAaPQ)AAI9904462","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/84979","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Layman, Donald K."]},{"key":"dc:creator","label":"Author","values":["Gautsch, Tracy Anne"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T22:31:11Z","10000-01-01","1998"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Nutritional Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Health Sciences, Rehabilitation and Therapy"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/84979","(MiAaPQ)AAI9904462"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The second specific aim of this research was to investigate the regulation of insulin-like growth factor binding protein-1 production following exercise. Prolonged exercise increased plasma and hepatic levels of IGFBP-1. Neither plasma insulin and glucose levels, nor meal composition altered IGFBP-1 production following exercise. Conversely, adaptation to treadmill running markedly suppressed IGFBP-1 production, suggesting a connection between exercise stress and IGFBP-1. Further, plasma corticosterone correlated to plasma IGFBP-1 in untrained and treadmill-adapted animals following exercise. However, pre-treatment with drugs that block corticosterone synthesis and bioactivity did not prevent IGFBP-1 from rising following exercise. These results demonstrate that upregulation of IGFBP-1 following exercise is corticosteroid-independent. Further research is needed to determine the chemical factor(s) inducing IGFBP-1 production following exercise.","Made available in DSpace on 2015-09-25T22:31:11Z (GMT). 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Prolonged exercise increased plasma and hepatic levels of IGFBP-1. Neither plasma insulin and glucose levels, nor meal composition altered IGFBP-1 production following exercise. Conversely, adaptation to treadmill running markedly suppressed IGFBP-1 production, suggesting a connection between exercise stress and IGFBP-1. Further, plasma corticosterone correlated to plasma IGFBP-1 in untrained and treadmill-adapted animals following exercise. However, pre-treatment with drugs that block corticosterone synthesis and bioactivity did not prevent IGFBP-1 from rising following exercise. These results demonstrate that upregulation of IGFBP-1 following exercise is corticosteroid-independent. Further research is needed to determine the chemical factor(s) inducing IGFBP-1 production following exercise.","Made available in DSpace on 2015-09-25T22:31:11Z (GMT). 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