{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/84969"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/84969","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Toward an Understanding of Interindividual Variation in Hydrogenotrophic Microbes in the Human Colon","abstract":"Chapter 4 describes the diversity of colonic SRB and methanogens in native African (NA), African American (AA) and Caucasian American (CA) healthy subjects. In this study, stool samples from NA, who were consuming a diet low in animal protein, versus AA and CA, with both cohorts consuming a typical Western diet, were used to examine the diversity of SRB and methanogenic microbes using PCR-based methods. Inferential and multivariate statistical analyses revealed that SRB populations in NA are more homogenous than in AA and that SRB communities in NA are distinguishable from those in AA and CA. Also, it was revealed that the African groups, NA and AA, harbor different Archaea populations than CA and that the microbial communities in NA and AA are distinguishable from those in CA. This observation is consistent with the hypothesis that interactions among ethnic background, diet and microbial mechanisms of H2 disposal may influence susceptibility to sporadic colorectal cancer. (Abstract shortened by UMI.).","abstract_html":"Chapter 4 describes the diversity of colonic SRB and methanogens in native African (NA), African American (AA) and Caucasian American (CA) healthy subjects. In this study, stool samples from NA, who were consuming a diet low in animal protein, versus AA and CA, with both cohorts consuming a typical Western diet, were used to examine the diversity of SRB and methanogenic microbes using PCR-based methods. Inferential and multivariate statistical analyses revealed that SRB populations in NA are more homogenous than in AA and that SRB communities in NA are distinguishable from those in AA and CA. Also, it was revealed that the African groups, NA and AA, harbor different Archaea populations than CA and that the microbial communities in NA and AA are distinguishable from those in CA. This observation is consistent with the hypothesis that interactions among ethnic background, diet and microbial mechanisms of H2 disposal may influence susceptibility to sporadic colorectal cancer. (Abstract shortened by UMI.).","abstract_has_math":false,"creators":["Nava-Morales, Gerardo Manuel"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Nutritional Sciences","degree_department":null,"school":null,"contributors":["Donovan, Sharon M."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T22:31:09Z","date_published":"2015-09-25T22:31:09Z","updated_at":"2026-07-22T22:26:24Z","subjects":["Biology, Microbiology"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI3399024"],"render_values":[{"text":"(MiAaPQ)AAI3399024","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/84969","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Donovan, Sharon M."]},{"key":"dc:creator","label":"Author","values":["Nava-Morales, Gerardo Manuel"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T22:31:09Z","10000-01-01","2009"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Nutritional Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biology, Microbiology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/84969","(MiAaPQ)AAI3399024"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Chapter 4 describes the diversity of colonic SRB and methanogens in native African (NA), African American (AA) and Caucasian American (CA) healthy subjects. In this study, stool samples from NA, who were consuming a diet low in animal protein, versus AA and CA, with both cohorts consuming a typical Western diet, were used to examine the diversity of SRB and methanogenic microbes using PCR-based methods. Inferential and multivariate statistical analyses revealed that SRB populations in NA are more homogenous than in AA and that SRB communities in NA are distinguishable from those in AA and CA. Also, it was revealed that the African groups, NA and AA, harbor different Archaea populations than CA and that the microbial communities in NA and AA are distinguishable from those in CA. This observation is consistent with the hypothesis that interactions among ethnic background, diet and microbial mechanisms of H2 disposal may influence susceptibility to sporadic colorectal cancer. (Abstract shortened by UMI.).","Made available in DSpace on 2015-09-25T22:31:09Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3399024.pdf: 3362616 bytes, checksum: b20141abc3c5f082695c5ad165b1bbaa (MD5) Previous issue date: 2009","Embargo set by: Seth Robbins for item 86250 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","220 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2009."]},{"key":"dc:title","label":"Title","values":["Toward an Understanding of Interindividual Variation in Hydrogenotrophic Microbes in the Human Colon"]}]}],"canonical_facts":{"dc:contributor":["Donovan, Sharon M."],"dc:creator":["Nava-Morales, Gerardo Manuel"],"dc:date":["2015-09-25T22:31:09Z","10000-01-01","2009"],"dc:description":["Chapter 4 describes the diversity of colonic SRB and methanogens in native African (NA), African American (AA) and Caucasian American (CA) healthy subjects. In this study, stool samples from NA, who were consuming a diet low in animal protein, versus AA and CA, with both cohorts consuming a typical Western diet, were used to examine the diversity of SRB and methanogenic microbes using PCR-based methods. Inferential and multivariate statistical analyses revealed that SRB populations in NA are more homogenous than in AA and that SRB communities in NA are distinguishable from those in AA and CA. Also, it was revealed that the African groups, NA and AA, harbor different Archaea populations than CA and that the microbial communities in NA and AA are distinguishable from those in CA. This observation is consistent with the hypothesis that interactions among ethnic background, diet and microbial mechanisms of H2 disposal may influence susceptibility to sporadic colorectal cancer. (Abstract shortened by UMI.).","Made available in DSpace on 2015-09-25T22:31:09Z (GMT). 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