Chromatographic, Spectroscopic and Crystallographic Investigations of Chiral Recognition Processes
type: CreativeWork
description: A number of experiments have been undertaken in order to determine, at the molecular level, the manner in which some of our recently developed low-molecular weight chiral selectors are capable of differentiating analyte enantiomers. When covalently linked to silica, these chiral selectors are capable of affording chromatographic enantioseparations. Series of homologous analytes were prepared and chromatographed on the chiral stationary phase of interest, in order to develop structure-selectivity relationships. Additionally, complexation with the chiral selector was investigated in solution (H NMR) and in the solid state (X-ray crystallography) utilizing soluble selector analogs and the analyte(s) of interest.
abstract: A number of experiments have been undertaken in order to determine, at the molecular level, the manner in which some of our recently developed low-molecular weight chiral selectors are capable of differentiating analyte enantiomers. When covalently linked to silica, these chiral selectors are capable of affording chromatographic enantioseparations. Series of homologous analytes were prepared and chromatographed on the chiral stationary phase of interest, in order to develop structure-selectivity relationships. Additionally, complexation with the chiral selector was investigated in solution (H NMR) and in the solid state (X-ray crystallography) utilizing soluble selector analogs and the analyte(s) of interest.
author: Koscho, Michael Edward
language: eng
keywords: Chemistry, Analytical
date published: 2015-09-25T22:14:33Z
date modified: 2026-07-22T22:26:23Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/84448