{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/84413"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/84413","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Characterization of Solution Species Relevant to the Peroxidase-Nadh Biochemical Oscillator","abstract":"The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly with NADH. Studies of kinetics of simultaneous processes of NADH acid-catalyzed decomposition, complexation, and oxidation in different environments were undertaken. It was observed that Fe2+ and Fe3+ were the only solution ions which caused a decrease in NADH decomposition rates, opposite to all other metal ions under investigation. The presence of metal ions accelerated NADH acid-catalyzed decomposition to a greater extent than NADH oxidation. Contrary to most literature sources, it was determined that the second, and not the first step of decomposition is rate-limiting. (Abstract shortened by UMI.).","abstract_html":"The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly with NADH. Studies of kinetics of simultaneous processes of NADH acid-catalyzed decomposition, complexation, and oxidation in different environments were undertaken. It was observed that Fe2+ and Fe3+ were the only solution ions which caused a decrease in NADH decomposition rates, opposite to all other metal ions under investigation. The presence of metal ions accelerated NADH acid-catalyzed decomposition to a greater extent than NADH oxidation. Contrary to most literature sources, it was determined that the second, and not the first step of decomposition is rate-limiting. (Abstract shortened by UMI.).","abstract_has_math":false,"creators":["Lvovich, Vadim Florentij"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Dissertation Abstracts International, Volume"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T22:14:21Z","date_published":"2015-09-25T22:14:21Z","updated_at":"2026-07-22T22:26:23Z","subjects":["Engineering, Chemical"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI9904529"],"render_values":[{"text":"(MiAaPQ)AAI9904529","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/84413","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Dissertation Abstracts International, Volume"]},{"key":"dc:creator","label":"Author","values":["Lvovich, Vadim Florentij"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T22:14:21Z","10000-01-01","1998"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Engineering, Chemical"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/84413","(MiAaPQ)AAI9904529"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly with NADH. Studies of kinetics of simultaneous processes of NADH acid-catalyzed decomposition, complexation, and oxidation in different environments were undertaken. It was observed that Fe2+ and Fe3+ were the only solution ions which caused a decrease in NADH decomposition rates, opposite to all other metal ions under investigation. The presence of metal ions accelerated NADH acid-catalyzed decomposition to a greater extent than NADH oxidation. Contrary to most literature sources, it was determined that the second, and not the first step of decomposition is rate-limiting. (Abstract shortened by UMI.).","Made available in DSpace on 2015-09-25T22:14:21Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 9904529.pdf: 8235668 bytes, checksum: 6a25eb913b69a6e31c4d6a3a6c1793ab (MD5) Previous issue date: 1998","Embargo set by: Seth Robbins for item 85694 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","203 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998."]},{"key":"dc:title","label":"Title","values":["Characterization of Solution Species Relevant to the Peroxidase-Nadh Biochemical Oscillator"]}]}],"canonical_facts":{"dc:contributor":["Dissertation Abstracts International, Volume"],"dc:creator":["Lvovich, Vadim Florentij"],"dc:date":["2015-09-25T22:14:21Z","10000-01-01","1998"],"dc:description":["The discovery of significance of iron-NADH complexation for the kinetics of NADH decomposition and oxidation led to an investigation of the influence of solution oxygen and biologically prominent metal ions on NADH degradation. Almost all metal ions under investigation appeared to complex quickly with NADH. Studies of kinetics of simultaneous processes of NADH acid-catalyzed decomposition, complexation, and oxidation in different environments were undertaken. It was observed that Fe2+ and Fe3+ were the only solution ions which caused a decrease in NADH decomposition rates, opposite to all other metal ions under investigation. The presence of metal ions accelerated NADH acid-catalyzed decomposition to a greater extent than NADH oxidation. Contrary to most literature sources, it was determined that the second, and not the first step of decomposition is rate-limiting. (Abstract shortened by UMI.).","Made available in DSpace on 2015-09-25T22:14:21Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 9904529.pdf: 8235668 bytes, checksum: 6a25eb913b69a6e31c4d6a3a6c1793ab (MD5) Previous issue date: 1998","Embargo set by: Seth Robbins for item 85694 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","203 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998."],"dc:identifier":["http://hdl.handle.net/2142/84413","(MiAaPQ)AAI9904529"],"dc:language":["eng"],"dc:subject":["Engineering, Chemical"],"dc:title":["Characterization of Solution Species Relevant to the Peroxidase-Nadh Biochemical Oscillator"],"dc:type":["text"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:23Z"}