{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/82474"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/82474","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Interactions Between Polyethylene Glycol Chains and Proteins and Chemically Selective Surfaces","abstract":"The results presented in this work directly demonstrate that far from presenting an inert and repulsive steric barrier, PEG brushes can interact differently with different chemically selective surfaces. Clearly, PEG is not an inert, simple polymer whose biological activity, especially, vis-a-vis proteins, can be solely described via descriptions of 'simple' polymers such as the excluded volume or scaling theory. 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Rather, these studies show that its biological response is coupled to the specific physico-chemical attributes of its segments and hence, to the competitive interactions between the solvent and other entities such as non-polar groups on the protein surface for the chain segments.","abstract_has_math":false,"creators":["Sheth, Shailesh Rameshchandra"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Chemical Engineering","degree_department":null,"school":null,"contributors":["Deborah Leckband"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T20:44:15Z","date_published":"2015-09-25T20:44:15Z","updated_at":"2026-07-22T22:26:18Z","subjects":["Chemistry, Physical"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI9953136"],"render_values":[{"text":"(MiAaPQ)AAI9953136","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/82474","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Deborah Leckband"]},{"key":"dc:creator","label":"Author","values":["Sheth, Shailesh Rameshchandra"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T20:44:15Z","10000-01-01","1999"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemical Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Chemistry, Physical"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/82474","(MiAaPQ)AAI9953136"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The results presented in this work directly demonstrate that far from presenting an inert and repulsive steric barrier, PEG brushes can interact differently with different chemically selective surfaces. 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