{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/81022"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/81022","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Surgical Breast Cancer Localization via Coherent Measurement of Endogenous Optical Properties","abstract":"These findings have been applied to the clinical problems of metastatic cell identification and biopsy needle localization. The latter is important due to the high rate of nondiagnostic tissue removal using current guidance techniques. Up to 10% of the approximately one million breast needle biopsies performed every year in the United States yield incorrect samples and inconclusive diagnoses, often resulting in additional surgical procedures. This poor outcome is due in large part to the inability of clinicians to spatially localize suspicious tissues during biopsy procedures. This problem has been addressed with the development of a clinically compatible fiber optic needle device capable of accurately measuring refractive index and scattering in situ. Preliminary intraoperative investigations with this device have yielded promising results.","abstract_html":"These findings have been applied to the clinical problems of metastatic cell identification and biopsy needle localization. The latter is important due to the high rate of nondiagnostic tissue removal using current guidance techniques. Up to 10% of the approximately one million breast needle biopsies performed every year in the United States yield incorrect samples and inconclusive diagnoses, often resulting in additional surgical procedures. This poor outcome is due in large part to the inability of clinicians to spatially localize suspicious tissues during biopsy procedures. This problem has been addressed with the development of a clinically compatible fiber optic needle device capable of accurately measuring refractive index and scattering in situ. Preliminary intraoperative investigations with this device have yielded promising results.","abstract_has_math":false,"creators":["Zysk, Adam Michael"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Electrical and Computer Engineering","degree_department":null,"school":null,"contributors":["Stephen Allen Boppart"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T20:09:15Z","date_published":"2015-09-25T20:09:15Z","updated_at":"2026-07-22T22:26:15Z","subjects":["Engineering, Biomedical"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI3270070"],"render_values":[{"text":"(MiAaPQ)AAI3270070","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/81022","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Stephen Allen Boppart"]},{"key":"dc:creator","label":"Author","values":["Zysk, Adam Michael"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T20:09:15Z","10000-01-01","2007"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical and Computer Engineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Engineering, Biomedical"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/81022","(MiAaPQ)AAI3270070"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["These findings have been applied to the clinical problems of metastatic cell identification and biopsy needle localization. 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