{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/80656"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/80656","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Magnetic Resonance Microscopy: 1. Four-Dimensional Spectral-Spatial Imaging. 2. Diffusional Effects in Magnetic Resonance Microscopy","abstract":"DESIRE (Diffusionally-Enhanced Signal Intensity and REsolution) is a new method for nuclear magnetic resonance (NMR) microscopy which couples a spatially localized region of saturated magnetization to the surrounding medium via translational diffusion of spins, resulting in amplification of the total saturated magnetization by several orders of magnitude over that obtained in the absence of diffusion. Combined with signal detection at narrow bandwidths of the order of the transverse relaxation rate, DESIRE results in greatly increased signal-to-noise relative to traditional NMR imaging techniques and has the potential for submicron resolution. Both time-dependent and steady-state simulations and analytic expressions will be presented, as well as a one-dimensional DESIRE experiment.","abstract_html":"DESIRE (Diffusionally-Enhanced Signal Intensity and REsolution) is a new method for nuclear magnetic resonance (NMR) microscopy which couples a spatially localized region of saturated magnetization to the surrounding medium via translational diffusion of spins, resulting in amplification of the total saturated magnetization by several orders of magnitude over that obtained in the absence of diffusion. Combined with signal detection at narrow bandwidths of the order of the transverse relaxation rate, DESIRE results in greatly increased signal-to-noise relative to traditional NMR imaging techniques and has the potential for submicron resolution. Both time-dependent and steady-state simulations and analytic expressions will be presented, as well as a one-dimensional DESIRE experiment.","abstract_has_math":false,"creators":["Hyslop, William Brian"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Physics","degree_department":null,"school":null,"contributors":["Lauterbur, Paul C.","Bob Clegg"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T20:03:28Z","date_published":"2015-09-25T20:03:28Z","updated_at":"2026-07-22T22:26:14Z","subjects":["Biophysics, Medical"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI9904485"],"render_values":[{"text":"(MiAaPQ)AAI9904485","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/80656","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Lauterbur, Paul C.","Bob Clegg"]},{"key":"dc:creator","label":"Author","values":["Hyslop, William Brian"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T20:03:28Z","10000-01-01","1998"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Physics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biophysics, Medical"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/80656","(MiAaPQ)AAI9904485"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["DESIRE (Diffusionally-Enhanced Signal Intensity and REsolution) is a new method for nuclear magnetic resonance (NMR) microscopy which couples a spatially localized region of saturated magnetization to the surrounding medium via translational diffusion of spins, resulting in amplification of the total saturated magnetization by several orders of magnitude over that obtained in the absence of diffusion. Combined with signal detection at narrow bandwidths of the order of the transverse relaxation rate, DESIRE results in greatly increased signal-to-noise relative to traditional NMR imaging techniques and has the potential for submicron resolution. Both time-dependent and steady-state simulations and analytic expressions will be presented, as well as a one-dimensional DESIRE experiment.","Made available in DSpace on 2015-09-25T20:03:28Z (GMT). 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