{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/79975"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/79975","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Influence of Thyroid Hormonal Status on Gene Expression for Calcium Channels in the Developing Olfactory Bulb and Cerebellum of the Postnatal Rat","abstract":"Based on our PCR results, it appears that the expression for these calcium channel genes is differentially regulated. In terms of development, the expression is tied more closely to development in the cerebellum than in the olfactory bulb. While expression appears to be regulated developmentally and by thyroid hormones, the effects are varied depending on both the tissue and channel. Taken together, this suggests that thyroid hormones due influence the expression of some calcium channels during postnatal development but the exact nature is unclear given the diversity of calcium channel expression in the mammalian brain.","abstract_html":"Based on our PCR results, it appears that the expression for these calcium channel genes is differentially regulated. In terms of development, the expression is tied more closely to development in the cerebellum than in the olfactory bulb. While expression appears to be regulated developmentally and by thyroid hormones, the effects are varied depending on both the tissue and channel. Taken together, this suggests that thyroid hormones due influence the expression of some calcium channels during postnatal development but the exact nature is unclear given the diversity of calcium channel expression in the mammalian brain.","abstract_has_math":false,"creators":["Brown, Chester M."],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Special Education","degree_department":null,"school":null,"contributors":["Esmail Meisami","Philip Best"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-09-25T19:54:46Z","date_published":"2015-09-25T19:54:46Z","updated_at":"2026-07-22T22:26:13Z","subjects":["Biology, Molecular"],"languages":["eng"],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(MiAaPQ)AAI3269849"],"render_values":[{"text":"(MiAaPQ)AAI3269849","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/79975","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Esmail Meisami","Philip Best"]},{"key":"dc:creator","label":"Author","values":["Brown, Chester M."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-09-25T19:54:46Z","10000-01-01","2007"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Special Education"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biology, Molecular"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/79975","(MiAaPQ)AAI3269849"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Based on our PCR results, it appears that the expression for these calcium channel genes is differentially regulated. 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