{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/78771"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/78771","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Effects of thermal stimuli during simulated hemorrhaging on aspects of cognitive performance","abstract":"Warming a hemorrhaging victim is the standard of care due to the adverse effects of combined hemorrhage and hypothermia on survival. However, it has been found that heating can be detrimental to the maintenance of arterial pressure, cerebral perfusion, and may also impact cognitive function. PURPOSE: To test the hypothesis that mildly heating an otherwise normothermic individual can be detrimental to cognitive function during a simulated mild hemorrhagic insult. METHODS: Nine men (mean ± SD: age, 29.9 ± 8.4 y; body mass, 79.4 ± 15.2 kg) underwent a randomized, crossover experimental design. Following 15 min of supine rest, 10 min of 30 mmHg of lower body negative pressure (LBNP) was applied to simulate a mild hemorrhagic challenge while subjects were normothermic. With LBNP continuing, subjects were exposed to mild whole-body heating (mean skin temperature (Tsk): 36.7 ± 0.5°C), skin surface cooling (Tsk: 29.6 ± 1.0°C), or remained thermoneutral (Tsk: 33.5 ± 0.6°C) for an additional 40 min via a water-perfused suit. A modified Erikson Flanker task was used as a measure of cognitive function. Affective valence and thermal sensations were also assessed. Upon completion of trials, subjects remained supine for 15 min for Tsk to return to baseline temperatures. RESULTS: Interaction between thermal perturbations and LBNP time did not reveal changes in cognitive function, as reflected in response accuracy (P = 0.19), reaction time (P = 0.09) or performance variability (P = 0.16) on the Flanker task. This suggests that LBNP with and without thermal perturbations had little influence on cognitive function. CONCLUSIONS: For the applied level of simulated hemorrhage (30 mmHg LBNP), these data suggest that mild heating of a hemorrhaging victim does not compromise cognitive function, while cooling is not beneficial. It remains unknown whether mild heating would be detrimental during a more profound simulated hemorrhagic challenge.","abstract_html":"Warming a hemorrhaging victim is the standard of care due to the adverse effects of combined hemorrhage and hypothermia on survival. However, it has been found that heating can be detrimental to the maintenance of arterial pressure, cerebral perfusion, and may also impact cognitive function. PURPOSE: To test the hypothesis that mildly heating an otherwise normothermic individual can be detrimental to cognitive function during a simulated mild hemorrhagic insult. METHODS: Nine men (mean ± SD: age, 29.9 ± 8.4 y; body mass, 79.4 ± 15.2 kg) underwent a randomized, crossover experimental design. Following 15 min of supine rest, 10 min of 30 mmHg of lower body negative pressure (LBNP) was applied to simulate a mild hemorrhagic challenge while subjects were normothermic. With LBNP continuing, subjects were exposed to mild whole-body heating (mean skin temperature (Tsk): 36.7 ± 0.5°C), skin surface cooling (Tsk: 29.6 ± 1.0°C), or remained thermoneutral (Tsk: 33.5 ± 0.6°C) for an additional 40 min via a water-perfused suit. A modified Erikson Flanker task was used as a measure of cognitive function. Affective valence and thermal sensations were also assessed. Upon completion of trials, subjects remained supine for 15 min for Tsk to return to baseline temperatures. RESULTS: Interaction between thermal perturbations and LBNP time did not reveal changes in cognitive function, as reflected in response accuracy (P = 0.19), reaction time (P = 0.09) or performance variability (P = 0.16) on the Flanker task. This suggests that LBNP with and without thermal perturbations had little influence on cognitive function. CONCLUSIONS: For the applied level of simulated hemorrhage (30 mmHg LBNP), these data suggest that mild heating of a hemorrhaging victim does not compromise cognitive function, while cooling is not beneficial. It remains unknown whether mild heating would be detrimental during a more profound simulated hemorrhagic challenge.","abstract_has_math":false,"creators":["Poh, Paula"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Kinesiology","degree_department":null,"school":null,"contributors":["Crandall, Craig G.","Petruzzello, Steven J.","Boppart, Marni D.","Horn, Gavin P."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2015,"date_issued":"2015-07-22T22:45:55Z","date_published":"2015-07-22T22:45:55Z","updated_at":"2026-07-22T22:26:12Z","subjects":["Thermoregulation","Trauma"],"languages":["en"],"rights":["Copyright 2015 Paula Yen Shan Poh"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/78771","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Crandall, Craig G.","Petruzzello, Steven J.","Boppart, Marni D.","Horn, Gavin P."]},{"key":"dc:creator","label":"Author","values":["Poh, Paula"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2015-07-22T22:45:55Z","2017-07-23T09:15:26Z","2015-05","2015-04-22","2015-5"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Thermoregulation","Trauma"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2015 Paula Yen Shan Poh"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/78771"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Warming a hemorrhaging victim is the standard of care due to the adverse effects of combined hemorrhage and hypothermia on survival. However, it has been found that heating can be detrimental to the maintenance of arterial pressure, cerebral perfusion, and may also impact cognitive function. PURPOSE: To test the hypothesis that mildly heating an otherwise normothermic individual can be detrimental to cognitive function during a simulated mild hemorrhagic insult. METHODS: Nine men (mean ± SD: age, 29.9 ± 8.4 y; body mass, 79.4 ± 15.2 kg) underwent a randomized, crossover experimental design. Following 15 min of supine rest, 10 min of 30 mmHg of lower body negative pressure (LBNP) was applied to simulate a mild hemorrhagic challenge while subjects were normothermic. With LBNP continuing, subjects were exposed to mild whole-body heating (mean skin temperature (Tsk): 36.7 ± 0.5°C), skin surface cooling (Tsk: 29.6 ± 1.0°C), or remained thermoneutral (Tsk: 33.5 ± 0.6°C) for an additional 40 min via a water-perfused suit. A modified Erikson Flanker task was used as a measure of cognitive function. Affective valence and thermal sensations were also assessed. Upon completion of trials, subjects remained supine for 15 min for Tsk to return to baseline temperatures. RESULTS: Interaction between thermal perturbations and LBNP time did not reveal changes in cognitive function, as reflected in response accuracy (P = 0.19), reaction time (P = 0.09) or performance variability (P = 0.16) on the Flanker task. This suggests that LBNP with and without thermal perturbations had little influence on cognitive function. CONCLUSIONS: For the applied level of simulated hemorrhage (30 mmHg LBNP), these data suggest that mild heating of a hemorrhaging victim does not compromise cognitive function, while cooling is not beneficial. It remains unknown whether mild heating would be detrimental during a more profound simulated hemorrhagic challenge.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-05-01","The student, Paula Poh, accepted the attached license on 2015-04-22 at 10:08.","The student, Paula Poh, submitted this Dissertation for approval on 2015-04-22 at 10:09.","This Dissertation was approved for publication on 2015-04-22 at 13:46.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8011 on 2015-07-22 at 14:26:06","Made available in DSpace on 2015-07-22T22:45:55Z (GMT). No. of bitstreams: 3 POH-DISSERTATION-2015.pdf: 1988825 bytes, checksum: b639a20efdf160bbb5bd758d9b44f7b0 (MD5) this one_EFFECTS OF THERMAL STIMULI DURING SIMULATED HEMORRHAGING ON ASPECTS OF COGNITIVE PERFORMANCE.docx: 1352367 bytes, checksum: 5882202cfe2bf4644bd1f0402ce29be2 (MD5) LICENSE.txt: 4206 bytes, checksum: 7c5942354b78917f55ccf526f56af5e7 (MD5) Previous issue date: 2015-04-22","Embargo set by: Seth Robbins for item 80012 Lift date: 2017-07-22T22:46:21Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system","Limited Restriction Lifted for Item 80012 on 2017-07-23T09:15:26Z."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Effects of thermal stimuli during simulated hemorrhaging on aspects of cognitive performance"]}]}],"canonical_facts":{"dc:contributor":["Crandall, Craig G.","Petruzzello, Steven J.","Boppart, Marni D.","Horn, Gavin P."],"dc:creator":["Poh, Paula"],"dc:date":["2015-07-22T22:45:55Z","2017-07-23T09:15:26Z","2015-05","2015-04-22","2015-5"],"dc:description":["Warming a hemorrhaging victim is the standard of care due to the adverse effects of combined hemorrhage and hypothermia on survival. However, it has been found that heating can be detrimental to the maintenance of arterial pressure, cerebral perfusion, and may also impact cognitive function. PURPOSE: To test the hypothesis that mildly heating an otherwise normothermic individual can be detrimental to cognitive function during a simulated mild hemorrhagic insult. METHODS: Nine men (mean ± SD: age, 29.9 ± 8.4 y; body mass, 79.4 ± 15.2 kg) underwent a randomized, crossover experimental design. Following 15 min of supine rest, 10 min of 30 mmHg of lower body negative pressure (LBNP) was applied to simulate a mild hemorrhagic challenge while subjects were normothermic. With LBNP continuing, subjects were exposed to mild whole-body heating (mean skin temperature (Tsk): 36.7 ± 0.5°C), skin surface cooling (Tsk: 29.6 ± 1.0°C), or remained thermoneutral (Tsk: 33.5 ± 0.6°C) for an additional 40 min via a water-perfused suit. A modified Erikson Flanker task was used as a measure of cognitive function. Affective valence and thermal sensations were also assessed. Upon completion of trials, subjects remained supine for 15 min for Tsk to return to baseline temperatures. RESULTS: Interaction between thermal perturbations and LBNP time did not reveal changes in cognitive function, as reflected in response accuracy (P = 0.19), reaction time (P = 0.09) or performance variability (P = 0.16) on the Flanker task. This suggests that LBNP with and without thermal perturbations had little influence on cognitive function. CONCLUSIONS: For the applied level of simulated hemorrhage (30 mmHg LBNP), these data suggest that mild heating of a hemorrhaging victim does not compromise cognitive function, while cooling is not beneficial. It remains unknown whether mild heating would be detrimental during a more profound simulated hemorrhagic challenge.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-05-01","The student, Paula Poh, accepted the attached license on 2015-04-22 at 10:08.","The student, Paula Poh, submitted this Dissertation for approval on 2015-04-22 at 10:09.","This Dissertation was approved for publication on 2015-04-22 at 13:46.","DSpace SAF Submission Ingestion Package generated from Vireo submission #8011 on 2015-07-22 at 14:26:06","Made available in DSpace on 2015-07-22T22:45:55Z (GMT). No. of bitstreams: 3 POH-DISSERTATION-2015.pdf: 1988825 bytes, checksum: b639a20efdf160bbb5bd758d9b44f7b0 (MD5) this one_EFFECTS OF THERMAL STIMULI DURING SIMULATED HEMORRHAGING ON ASPECTS OF COGNITIVE PERFORMANCE.docx: 1352367 bytes, checksum: 5882202cfe2bf4644bd1f0402ce29be2 (MD5) LICENSE.txt: 4206 bytes, checksum: 7c5942354b78917f55ccf526f56af5e7 (MD5) Previous issue date: 2015-04-22","Embargo set by: Seth Robbins for item 80012 Lift date: 2017-07-22T22:46:21Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system","Limited Restriction Lifted for Item 80012 on 2017-07-23T09:15:26Z."],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/2142/78771"],"dc:language":["en"],"dc:rights":["Copyright 2015 Paula Yen Shan Poh"],"dc:subject":["Thermoregulation","Trauma"],"dc:title":["Effects of thermal stimuli during simulated hemorrhaging on aspects of cognitive performance"],"dc:type":["text"],"thesis:degree_discipline":["Kinesiology"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:12Z"}