Intercalary Regeneration in Larval Ambystoma Limbs: The Origin of Skeletal Structures and The Non-Segmental Organization of Morphogenetic Information
type: CreativeWork
description: Urodele limbs are able to regulate for intercalary deletions created when distal regeneration blastemas are grafted to a more proximal level. Using several morphological markers, pigmentation differences between white and dark axolotls, and the difference in nucleolar number between diploid and triploid animals, I show that the entire intercalary regenerate is derived from the stump when wrist or tarsus blastemas are grafted to the mid-stylopodium of the fore- or hindlimb. The transplanted prospective autopodium forms no more than would be expected in situ. Thus, the rule of distal transformation is not violated during intercalary regeneration in salamanders.
abstract: Urodele limbs are able to regulate for intercalary deletions created when distal regeneration blastemas are grafted to a more proximal level. Using several morphological markers, pigmentation differences between white and dark axolotls, and the difference in nucleolar number between diploid and triploid animals, I show that the entire intercalary regenerate is derived from the stump when wrist or tarsus blastemas are grafted to the mid-stylopodium of the fore- or hindlimb. The transplanted prospective autopodium forms no more than would be expected in situ. Thus, the rule of distal transformation is not violated during intercalary regeneration in salamanders.
author: Pescitelli, Maurice Joseph, Jr.
language: eng
keywords: Biology, General
date published: 2015-05-14T15:08:33Z
date modified: 2026-07-22T22:26:11Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/77577