Synthetic Micellar Complexes of Apolipoprotein a-I With Lipids as Substrates for Human Lecithin Cholesterol Acyltransferase
Micellar lipid-apolipoprotein A-I (apo A-I) complexes were produced by adding human apo A-I to lipid dispersions containing sodium cholate. The lipid mixtures included dimyristoyl phosphatidylcholine (DMPC), dipalmitoyl phosphatidylcholine (DPPC), and egg phosphatidylcholine (egg-PC). The formation of complexes was examined at increasing cholesterol contents with DPPC, and at 20 mole % cholesterol contents for DMPC, DPPC, and egg-PC.
University of Illinois - Urbana-Champaign
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University of Illinois at Urbana-Champaign