Conjugated Estrogen Receptor Probes: An Evaluation of Fluorophores, Photolabile Groups, Estrogenic Ligands, and the Nature of the Attaching Chain
A good correlation exists between the level of estrogen receptor in breast tumors, and their responsiveness to hormone therapy. However, the correlation is not perfect; about 40% of women with measurable tumor receptor levels do not respond to hormone treatment. The work described herein was undertaken in order to improve the predictability of hormone responsiveness.
University of Illinois - Urbana-Champaign
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University of Illinois at Urbana-Champaign