Advances in Fast Atom Bombardment Mass-Spectrometry (Glycosphingolipids, Nucleotides, Markers, Negative Ion)
type: CreativeWork
description: The capabilities and limitations of the recently introduced technique of fast atom bombardment mass spectrometry were explored. A comparison of fast atom bombardment and field desorption mass spectrometry was made to determine relative sensitivity and applicability. A series of glycosphingolipids and a series of protected oligonucleotides of known structure were analyzed to ascertain the potential utility of fast atom bombardment mass spectrometry in the structural elucidation of novel compounds in these classes. Negative ion mass markers, necessary for accurate mass measurements of the aforementioned classes of compounds and in newly proposed scanning accurate mass measurement methods, were also developed.
abstract: The capabilities and limitations of the recently introduced technique of fast atom bombardment mass spectrometry were explored. A comparison of fast atom bombardment and field desorption mass spectrometry was made to determine relative sensitivity and applicability. A series of glycosphingolipids and a series of protected oligonucleotides of known structure were analyzed to ascertain the potential utility of fast atom bombardment mass spectrometry in the structural elucidation of novel compounds in these classes. Negative ion mass markers, necessary for accurate mass measurements of the aforementioned classes of compounds and in newly proposed scanning accurate mass measurement methods, were also developed.
author: Hemling, Mark Elliott
keywords: Chemistry, Analytical
date published: 2014-12-15T23:18:40Z
date modified: 2026-07-22T22:26:02Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/70326