{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/70024"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/70024","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"An Investigation of Factors Affecting the Pyridoxine Requirement of Postpubertal Gilts (Metabolism, Phosphorylase, Muscle)","abstract":"Various nutritional factors were investigated with respect to their effect on the dietary B6 requirement of swine. Factors investigated included the extent and significance of B6 storage in muscle tissue, the effect of a riboflavin deficiency on B6 metabolism and thus on B6 status, and finally the contribution of gut microbial B6 synthesis to the pool of absorbable B6 and its subsequent utilization by the host animal. In addition to these specific factors, biochemical criteria were evaluated for use as measures of B6 nutritional status and the current estimate of the B6 requirement was reevaluated. In addition to swine, mice were used in some experiments as model animals.","abstract_html":"Various nutritional factors were investigated with respect to their effect on the dietary B6 requirement of swine. Factors investigated included the extent and significance of B6 storage in muscle tissue, the effect of a riboflavin deficiency on B6 metabolism and thus on B6 status, and finally the contribution of gut microbial B6 synthesis to the pool of absorbable B6 and its subsequent utilization by the host animal. In addition to these specific factors, biochemical criteria were evaluated for use as measures of B6 nutritional status and the current estimate of the B6 requirement was reevaluated. In addition to swine, mice were used in some experiments as model animals.","abstract_has_math":false,"creators":["Russell, Louis Edward"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Animal Sciences","degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2014,"date_issued":"2014-12-15T21:00:58Z","date_published":"2014-12-15T21:00:58Z","updated_at":"2026-07-22T22:26:02Z","subjects":["Agriculture, Animal Culture and Nutrition"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["(UMI)AAI8502286"],"render_values":[{"text":"(UMI)AAI8502286","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/70024","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Russell, Louis Edward"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2014-12-15T21:00:58Z","10000-01-01","1984"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Animal Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Agriculture, Animal Culture and Nutrition"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/70024","(UMI)AAI8502286"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Various nutritional factors were investigated with respect to their effect on the dietary B6 requirement of swine. Factors investigated included the extent and significance of B6 storage in muscle tissue, the effect of a riboflavin deficiency on B6 metabolism and thus on B6 status, and finally the contribution of gut microbial B6 synthesis to the pool of absorbable B6 and its subsequent utilization by the host animal. In addition to these specific factors, biochemical criteria were evaluated for use as measures of B6 nutritional status and the current estimate of the B6 requirement was reevaluated. In addition to swine, mice were used in some experiments as model animals.","Muscle tissue was found to have a great capacity to accumulate B6 when dietary excesses of the vitamin were consumed. It is suggested that the affinity of B6 for proteins within a given tissue may be an important aspect controlling the release of B6 from tissues; however, the mechanism is not fully understood. In these experiments, a B6 deficiency was ineffective in triggering the release of muscle B6.","In swine, the erythrocyte glutamate-oxaloacetate transaminase activity coefficient (EGOT-Ac) appeared to be a reliable index of B6 status in short-term, controlled experiments (16 weeks). During an extended depletion period ((GREATERTHEQ) 32 weeks), the EGOT-Ac appeared to lose some sensitivity to dietary B6 intake.","Biochemical changes indicative of a B6 deficiency were observed in mice fed a riboflavin-deficient diet. Thus, it is suggested that B6 metabolism may be impaired in riboflavin-deficient animals. It was also noted that the B6 requirement is positively correlated to dietary protein concentration.","In growing pigs, recovery of dietary B6 in the urine as 4-pyridoxic acid was 105%. 4-Pyridoxic acid excretion was not affected by high dietary sulfamethazine but only by the amount of B6 ingested. It was concluded that microbially synthesized B6 from the intestine does not account for a substantial percentage of the total B6 absorbed.","The current recommendation of 1.8 mg B6/day for postpubertal gilts appears to be inadequate.","Made available in DSpace on 2014-12-15T21:00:58Z (GMT). No. of bitstreams: 1 8502286.pdf: 3693563 bytes, checksum: d4fa775034aaef222dca4cc1d129c9cf (MD5) Previous issue date: 1984","Embargo set by: Seth Robbins for item 70190 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","111 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984."]},{"key":"dc:title","label":"Title","values":["An Investigation of Factors Affecting the Pyridoxine Requirement of Postpubertal Gilts (Metabolism, Phosphorylase, Muscle)"]}]}],"canonical_facts":{"dc:creator":["Russell, Louis Edward"],"dc:date":["2014-12-15T21:00:58Z","10000-01-01","1984"],"dc:description":["Various nutritional factors were investigated with respect to their effect on the dietary B6 requirement of swine. Factors investigated included the extent and significance of B6 storage in muscle tissue, the effect of a riboflavin deficiency on B6 metabolism and thus on B6 status, and finally the contribution of gut microbial B6 synthesis to the pool of absorbable B6 and its subsequent utilization by the host animal. In addition to these specific factors, biochemical criteria were evaluated for use as measures of B6 nutritional status and the current estimate of the B6 requirement was reevaluated. In addition to swine, mice were used in some experiments as model animals.","Muscle tissue was found to have a great capacity to accumulate B6 when dietary excesses of the vitamin were consumed. It is suggested that the affinity of B6 for proteins within a given tissue may be an important aspect controlling the release of B6 from tissues; however, the mechanism is not fully understood. In these experiments, a B6 deficiency was ineffective in triggering the release of muscle B6.","In swine, the erythrocyte glutamate-oxaloacetate transaminase activity coefficient (EGOT-Ac) appeared to be a reliable index of B6 status in short-term, controlled experiments (16 weeks). During an extended depletion period ((GREATERTHEQ) 32 weeks), the EGOT-Ac appeared to lose some sensitivity to dietary B6 intake.","Biochemical changes indicative of a B6 deficiency were observed in mice fed a riboflavin-deficient diet. Thus, it is suggested that B6 metabolism may be impaired in riboflavin-deficient animals. It was also noted that the B6 requirement is positively correlated to dietary protein concentration.","In growing pigs, recovery of dietary B6 in the urine as 4-pyridoxic acid was 105%. 4-Pyridoxic acid excretion was not affected by high dietary sulfamethazine but only by the amount of B6 ingested. It was concluded that microbially synthesized B6 from the intestine does not account for a substantial percentage of the total B6 absorbed.","The current recommendation of 1.8 mg B6/day for postpubertal gilts appears to be inadequate.","Made available in DSpace on 2014-12-15T21:00:58Z (GMT). No. of bitstreams: 1 8502286.pdf: 3693563 bytes, checksum: d4fa775034aaef222dca4cc1d129c9cf (MD5) Previous issue date: 1984","Embargo set by: Seth Robbins for item 70190 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs","U of I Only","111 p.","Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984."],"dc:identifier":["http://hdl.handle.net/2142/70024","(UMI)AAI8502286"],"dc:subject":["Agriculture, Animal Culture and Nutrition"],"dc:title":["An Investigation of Factors Affecting the Pyridoxine Requirement of Postpubertal Gilts (Metabolism, Phosphorylase, Muscle)"],"dc:type":["text"],"thesis:degree_discipline":["Animal Sciences"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:26:02Z"}