{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/45541"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/45541","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Prostate tissue diagnosis using quantitative phase imaging techniques","abstract":"Restriction data tranferred 2014-07-01T11:20:34-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-08-22 11:49:27 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","abstract_html":"Restriction data tranferred 2014-07-01T11:20:34-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-08-22 11:49:27 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","abstract_has_math":false,"creators":["Sridharan, Shamira"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Bioengineering","degree_department":null,"school":null,"contributors":["Popescu, Gabriel"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2013,"date_issued":"2013-08-22T16:47:10Z","date_published":"2013-08-22T16:47:10Z","updated_at":"2026-07-22T22:25:36Z","subjects":["prostate","cancer","quantitative phase imaging (QPI)","spatial light interference microscopy (SLIM)","Gleason grading","nucleus"],"languages":["en"],"rights":["Copyright 2013 Shamira Sridharan"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/45541","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Popescu, Gabriel"]},{"key":"dc:creator","label":"Author","values":["Sridharan, Shamira"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2013-08-22T16:47:10Z","2015-08-22T10:00:54Z","2013-08"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Bioengineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["prostate","cancer","quantitative phase imaging (QPI)","spatial light interference microscopy (SLIM)","Gleason grading","nucleus"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2013 Shamira Sridharan"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/45541"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Restriction data tranferred 2014-07-01T11:20:34-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-08-22 11:49:27 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Seth Robbins (srobbins@illinois.edu) on 2013-08-22T16:49:31Z Item is restricted until 2015-08-22T16:49:27Z","U of I Only Restriction Lifted for Item 45523 on 2015-08-22T10:00:54Z.","The lifetime risk of a man getting diagnosed with prostate cancer is 1 in 6. The diagnosis is made by the pathologist using staining methods and immunohistochemical markers to detect malignancy on tissue biopsy sections. Quantitative phase imaging methods eliminate the need for stains and markers. It exploits the intrinsic contrast from the refractive index differences in tissue. The quantitative nature of this technique eliminates inter-observer variability. QPI is sensitive to sub-nanometer level changes in tissue architecture. Light scattering information is also accessible from QPI images since it records both the amplitude and the phase of light that passes through the sample. In this thesis, I show the ability of QPI to distinguish between cancerous and benign samples. I also show its ability to detect changes in stroma and nuclei through different stages of prostate cancer progression that are not detectable using conventional methods.","Item withdrawn by Alexis Thompson (athmpsn1@illinois.edu) on 2013-07-11T19:31:27Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Sridharan_Shamira.pdf: 2152468 bytes, checksum: c23ceb7df8aff17e68389ebefa6e5e74 (MD5)","Made available in DSpace on 2013-08-22T16:47:10Z (GMT). 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