{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/42299"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/42299","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Bioparticle capture and sensing utilizing nanograss based microfluidic devices","abstract":"For the past few decades, biosensors have been developed at a steady pace and played a crucial role in medical practices and many other biomedical applications. Upon performing a survey of desirable sensor properties such as low cost, high sensitivity, fabrication process, and time to result, a nanograss embedded microfluidic device emerged as a very attractive candidate for an electrochemical impedance spectroscopy (EIS) based biosensor. Such a sensing device is expected to perform direct sensing quickly with high sensitivity, and at low cost. In this work, the nanograss fabrication process is illustrated in detail. Then nanograss substrate itself is characterized by multiple approaches. In addition, COMSOL Multiphysics is used for finite element simulation of the flow through the microfluidic chamber. The EIS method is used to evaluate the capture and sensing ability of the fabricated nanograss embedded microfluidic device. The nanograss devices are shown to be able to capture and sense a few particles/µL, indicating that the nanograss devices could be used as next-generation biosensors.","abstract_html":"For the past few decades, biosensors have been developed at a steady pace and played a crucial role in medical practices and many other biomedical applications. Upon performing a survey of desirable sensor properties such as low cost, high sensitivity, fabrication process, and time to result, a nanograss embedded microfluidic device emerged as a very attractive candidate for an electrochemical impedance spectroscopy (EIS) based biosensor. Such a sensing device is expected to perform direct sensing quickly with high sensitivity, and at low cost. In this work, the nanograss fabrication process is illustrated in detail. Then nanograss substrate itself is characterized by multiple approaches. In addition, COMSOL Multiphysics is used for finite element simulation of the flow through the microfluidic chamber. The EIS method is used to evaluate the capture and sensing ability of the fabricated nanograss embedded microfluidic device. The nanograss devices are shown to be able to capture and sense a few particles/µL, indicating that the nanograss devices could be used as next-generation biosensors.","abstract_has_math":false,"creators":["Ni, Hengkan"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Electrical & Computer Engr","degree_department":null,"school":null,"contributors":["Bashir, Rashid"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2013,"date_issued":"2013-02-03T19:30:45Z","date_published":"2013-02-03T19:30:45Z","updated_at":"2026-07-22T22:25:33Z","subjects":["Nanograss","Biosensor","Electrochemical Impedance Sensing (EIS)"],"languages":["en"],"rights":["Copyright 2012 Hengkan Ni"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/42299","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Bashir, Rashid"]},{"key":"dc:creator","label":"Author","values":["Ni, Hengkan"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2013-02-03T19:30:45Z","2012-12"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical & Computer Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Nanograss","Biosensor","Electrochemical Impedance Sensing (EIS)"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2012 Hengkan Ni"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/42299"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["For the past few decades, biosensors have been developed at a steady pace and played a crucial role in medical practices and many other biomedical applications. Upon performing a survey of desirable sensor properties such as low cost, high sensitivity, fabrication process, and time to result, a nanograss embedded microfluidic device emerged as a very attractive candidate for an electrochemical impedance spectroscopy (EIS) based biosensor. Such a sensing device is expected to perform direct sensing quickly with high sensitivity, and at low cost. In this work, the nanograss fabrication process is illustrated in detail. Then nanograss substrate itself is characterized by multiple approaches. In addition, COMSOL Multiphysics is used for finite element simulation of the flow through the microfluidic chamber. The EIS method is used to evaluate the capture and sensing ability of the fabricated nanograss embedded microfluidic device. 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Such a sensing device is expected to perform direct sensing quickly with high sensitivity, and at low cost. In this work, the nanograss fabrication process is illustrated in detail. Then nanograss substrate itself is characterized by multiple approaches. In addition, COMSOL Multiphysics is used for finite element simulation of the flow through the microfluidic chamber. The EIS method is used to evaluate the capture and sensing ability of the fabricated nanograss embedded microfluidic device. The nanograss devices are shown to be able to capture and sense a few particles/µL, indicating that the nanograss devices could be used as next-generation biosensors.","Item withdrawn by Alexis Thompson (athmpsn1@illinois.edu) on 2012-12-05T16:05:57Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Ni_Hengkan.pdf: 1850431 bytes, checksum: 7076afd0d88542a404504c8407aa8b26 (MD5)","Made available in DSpace on 2013-02-03T19:30:45Z (GMT). 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