{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/30847"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/30847","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Physical models of protein folding within the energy landscape theory","abstract":"The energy landscape theory of protein fol9.ing is based on a statistical description of a protein's complex potential energy surface. Individual folding events are sampled from an ensemble of possible routes on the landscape. The theory suggests that the landscape of a protein can be described as that of a partially random heteropolymer with a rugged, yet funnelled landscape towards the native structure. The quantitative aspects of folding are developed using tools from the statistical mechanics of disordered systems, polymers, and phase transitions of finite systems. The theory provides an interpretation of results from fast folding experiments as well as minimalist models used in computer simulations.","abstract_html":"The energy landscape theory of protein fol9.ing is based on a statistical description of a protein's complex potential energy surface. Individual folding events are sampled from an ensemble of possible routes on the landscape. The theory suggests that the landscape of a protein can be described as that of a partially random heteropolymer with a rugged, yet funnelled landscape towards the native structure. The quantitative aspects of folding are developed using tools from the statistical mechanics of disordered systems, polymers, and phase transitions of finite systems. The theory provides an interpretation of results from fast folding experiments as well as minimalist models used in computer simulations.","abstract_has_math":false,"creators":["Plotkin, Steven S."],"institution":null,"degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Physics","degree_department":null,"school":null,"contributors":["Wolynes, P.G."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012-05-15T16:19:14Z","date_published":"2012-05-15T16:19:14Z","updated_at":"2026-07-22T22:25:29Z","subjects":["protein folding","energy landscape theory","potential energy surface","partially random heteropolymer"],"languages":["en"],"rights":["©1998 Plotkin"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["4161509"],"render_values":[{"text":"4161509","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/30847","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Wolynes, P.G."]},{"key":"dc:creator","label":"Author","values":["Plotkin, Steven S."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2012-05-15T16:19:14Z","10000-01-01","1998"]},{"key":"dc:type","label":"Dc Type","values":["Dissertation / Thesis","text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Physics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["protein folding","energy landscape theory","potential energy surface","partially random heteropolymer"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["©1998 Plotkin"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/30847","4161509"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The energy landscape theory of protein fol9.ing is based on a statistical description of a protein's complex potential energy surface. Individual folding events are sampled from an ensemble of possible routes on the landscape. The theory suggests that the landscape of a protein can be described as that of a partially random heteropolymer with a rugged, yet funnelled landscape towards the native structure. The quantitative aspects of folding are developed using tools from the statistical mechanics of disordered systems, polymers, and phase transitions of finite systems. The theory provides an interpretation of results from fast folding experiments as well as minimalist models used in computer simulations.","Submitted by William Weathers (weathrs2@illinois.edu) on 2012-05-15T16:19:13Z No. of bitstreams: 1 1998_plotkin.pdf: 6768296 bytes, checksum: f6fb1a4ca094277458e45b46d1c6fac6 (MD5)","Made available in DSpace on 2012-05-15T16:19:14Z (GMT). No. of bitstreams: 1 1998_plotkin.pdf: 6768296 bytes, checksum: f6fb1a4ca094277458e45b46d1c6fac6 (MD5) Previous issue date: 1998","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by William Weathers (weathrs2@illinois.edu) on 2012-05-15T16:19:14Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:34:42-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: Thesis","Thesis","U of I Only"]},{"key":"dc:title","label":"Title","values":["Physical models of protein folding within the energy landscape theory"]}]}],"canonical_facts":{"dc:contributor":["Wolynes, P.G."],"dc:creator":["Plotkin, Steven S."],"dc:date":["2012-05-15T16:19:14Z","10000-01-01","1998"],"dc:description":["The energy landscape theory of protein fol9.ing is based on a statistical description of a protein's complex potential energy surface. Individual folding events are sampled from an ensemble of possible routes on the landscape. The theory suggests that the landscape of a protein can be described as that of a partially random heteropolymer with a rugged, yet funnelled landscape towards the native structure. The quantitative aspects of folding are developed using tools from the statistical mechanics of disordered systems, polymers, and phase transitions of finite systems. The theory provides an interpretation of results from fast folding experiments as well as minimalist models used in computer simulations.","Submitted by William Weathers (weathrs2@illinois.edu) on 2012-05-15T16:19:13Z No. of bitstreams: 1 1998_plotkin.pdf: 6768296 bytes, checksum: f6fb1a4ca094277458e45b46d1c6fac6 (MD5)","Made available in DSpace on 2012-05-15T16:19:14Z (GMT). No. of bitstreams: 1 1998_plotkin.pdf: 6768296 bytes, checksum: f6fb1a4ca094277458e45b46d1c6fac6 (MD5) Previous issue date: 1998","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by William Weathers (weathrs2@illinois.edu) on 2012-05-15T16:19:14Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:34:42-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: Thesis","Thesis","U of I Only"],"dc:identifier":["http://hdl.handle.net/2142/30847","4161509"],"dc:language":["en"],"dc:rights":["©1998 Plotkin"],"dc:subject":["protein folding","energy landscape theory","potential energy surface","partially random heteropolymer"],"dc:title":["Physical models of protein folding within the energy landscape theory"],"dc:type":["Dissertation / Thesis","text"],"thesis:degree_discipline":["Physics"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."]},"updated_at":"2026-07-22T22:25:29Z"}