{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/23330"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/23330","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Analyses and predictions of ultrasound interactions with model biomembrane systems via two-state transition model","abstract":"Low intensity ultrasound (approximately 10$\\sp{-6}$ W/cm$\\sp2$) in the frequency range of 0.5 MHz to 5.0 MHz was employed to investigate biomembrane structural relaxation kinetics via absorption and velocity dispersion spectroscopy. The multilamellar vesicles utilized in this investigation were either composed of pure phospholipids or mixtures of phospholipids and small molar fractions of protein gramicidin. The experimental findings reveal enhanced ultrasound interactions near to the lipid phase transition temperature. The enhanced ultrasound absorption spectra closely resemble single relaxation spectra, suggesting that the membrane constituents undergo a simple two-state transition. The temperature dependence of the relaxation frequency is followed with the combined aid of the absorption and velocity dispersion spectrum. Thermodynamic and electrical capacitor two-state transition models are developed to help describe the observed phenomena and to predict to a reasonable degree of accuracy the enhanced findings promoted by ultrasound.","abstract_html":"Low intensity ultrasound (approximately 10$\\sp{-6}$ W/cm$\\sp2$) in the frequency range of 0.5 MHz to 5.0 MHz was employed to investigate biomembrane structural relaxation kinetics via absorption and velocity dispersion spectroscopy. The multilamellar vesicles utilized in this investigation were either composed of pure phospholipids or mixtures of phospholipids and small molar fractions of protein gramicidin. The experimental findings reveal enhanced ultrasound interactions near to the lipid phase transition temperature. The enhanced ultrasound absorption spectra closely resemble single relaxation spectra, suggesting that the membrane constituents undergo a simple two-state transition. The temperature dependence of the relaxation frequency is followed with the combined aid of the absorption and velocity dispersion spectrum. Thermodynamic and electrical capacitor two-state transition models are developed to help describe the observed phenomena and to predict to a reasonable degree of accuracy the enhanced findings promoted by ultrasound.","abstract_has_math":true,"creators":["Tata, Darayash Burjor"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Biophysics and Computational Biology","degree_department":null,"school":null,"contributors":["Dunn, Floyd"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-05-07T14:10:19Z","date_published":"2011-05-07T14:10:19Z","updated_at":"2026-07-22T22:25:21Z","subjects":["Chemistry, Physical","Engineering, Biomedical","Physics, Acoustics"],"languages":["eng"],"rights":["Copyright 1991 Tata, Darayash Burjor"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9211009","(UMI)AAI9211009"],"render_values":[{"text":"AAI9211009","href":null,"code":true},{"text":"(UMI)AAI9211009","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/23330","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Dunn, Floyd"]},{"key":"dc:creator","label":"Author","values":["Tata, Darayash Burjor"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2011-05-07T14:10:19Z","10000-01-01","1991"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biophysics and Computational Biology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Chemistry, Physical","Engineering, Biomedical","Physics, Acoustics"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 1991 Tata, Darayash Burjor"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9211009","(UMI)AAI9211009","http://hdl.handle.net/2142/23330"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Low intensity ultrasound (approximately 10$\\sp{-6}$ W/cm$\\sp2$) in the frequency range of 0.5 MHz to 5.0 MHz was employed to investigate biomembrane structural relaxation kinetics via absorption and velocity dispersion spectroscopy. The multilamellar vesicles utilized in this investigation were either composed of pure phospholipids or mixtures of phospholipids and small molar fractions of protein gramicidin. The experimental findings reveal enhanced ultrasound interactions near to the lipid phase transition temperature. The enhanced ultrasound absorption spectra closely resemble single relaxation spectra, suggesting that the membrane constituents undergo a simple two-state transition. The temperature dependence of the relaxation frequency is followed with the combined aid of the absorption and velocity dispersion spectrum. Thermodynamic and electrical capacitor two-state transition models are developed to help describe the observed phenomena and to predict to a reasonable degree of accuracy the enhanced findings promoted by ultrasound.","Made available in DSpace on 2011-05-07T14:10:19Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9211009.pdf: 2077487 bytes, checksum: c46c3de15132af5cd8332601eff3c9c6 (MD5) Previous issue date: 1991","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T15:03:45Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:30:24-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission","ETDs are only available to UIUC Users without author permission","U of I Only"]},{"key":"dc:title","label":"Title","values":["Analyses and predictions of ultrasound interactions with model biomembrane systems via two-state transition model"]}]}],"canonical_facts":{"dc:contributor":["Dunn, Floyd"],"dc:creator":["Tata, Darayash Burjor"],"dc:date":["2011-05-07T14:10:19Z","10000-01-01","1991"],"dc:description":["Low intensity ultrasound (approximately 10$\\sp{-6}$ W/cm$\\sp2$) in the frequency range of 0.5 MHz to 5.0 MHz was employed to investigate biomembrane structural relaxation kinetics via absorption and velocity dispersion spectroscopy. The multilamellar vesicles utilized in this investigation were either composed of pure phospholipids or mixtures of phospholipids and small molar fractions of protein gramicidin. The experimental findings reveal enhanced ultrasound interactions near to the lipid phase transition temperature. The enhanced ultrasound absorption spectra closely resemble single relaxation spectra, suggesting that the membrane constituents undergo a simple two-state transition. The temperature dependence of the relaxation frequency is followed with the combined aid of the absorption and velocity dispersion spectrum. Thermodynamic and electrical capacitor two-state transition models are developed to help describe the observed phenomena and to predict to a reasonable degree of accuracy the enhanced findings promoted by ultrasound.","Made available in DSpace on 2011-05-07T14:10:19Z (GMT). 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