{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/22662"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/22662","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"High-resolution nuclear magnetic resonance studies of lipids and model membranes","abstract":"\"This thesis is devoted to the new applications of high resolution $\\sp1$H and $\\sp{13}$C \"\"magic angle sample spinning\"\" (MASS) nuclear magnetic resonance (NMR) techniques to the study of model and biological membranes. Since the resolution of $\\sp1$H and $\\sp{13}$C MASS NMR spectra from multilamella and hexagonal-II phase is the same or even better than that obtained with sonicated liquid-crystalline system, the dynamics of membranes can be studied through measuring linewidth, T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$ relaxation rates for numerous, resolved, single carbon, or individual proton sites by MASS NMR techniques. Chapter II provides a summary of the theoretical background of MASS NMR of model membranes and spin-lattice relaxations of bilayer system. Chapter III discusses the application of high resolution $\\sp1$H MASS NMR to the study of a variety of lipids. The chemical shift assignments, order parameters, and relaxation times (T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$) can be determined for these lipids. Chapter IV reports the study of a typical model system for lipid-protein interaction in membrane, gramicidin-phospholipid, by using $\\sp1$H MASS NMR techniques. The dynamic picture of phospholipid-polypeptide interaction is obtained. Chapter V discusses the application of high resolution $\\sp1$H and $\\sp{13}$C MASS NMR spectroscopy to the study of thylakoid lipids, monogalactosyldiacyglycerol (MGDG), digalactosyldiacylglycerol (DGDG), and sulphoquinovosyldiacylglycerol (SQDG). The chemical shift assignments and the dynamic picture is derived for these thylakoid lipids. Results on studying a variety of phospholipids and sphingomyelin by using $\\sp{13}$C MASS NMR spectroscopy are presented in Chapter VI.\"","abstract_html":""This thesis is devoted to the new applications of high resolution $\\sp1$H and $\\sp{13}$C ""magic angle sample spinning"" (MASS) nuclear magnetic resonance (NMR) techniques to the study of model and biological membranes. Since the resolution of $\\sp1$H and $\\sp{13}$C MASS NMR spectra from multilamella and hexagonal-II phase is the same or even better than that obtained with sonicated liquid-crystalline system, the dynamics of membranes can be studied through measuring linewidth, T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$ relaxation rates for numerous, resolved, single carbon, or individual proton sites by MASS NMR techniques. Chapter II provides a summary of the theoretical background of MASS NMR of model membranes and spin-lattice relaxations of bilayer system. Chapter III discusses the application of high resolution $\\sp1$H MASS NMR to the study of a variety of lipids. The chemical shift assignments, order parameters, and relaxation times (T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$) can be determined for these lipids. Chapter IV reports the study of a typical model system for lipid-protein interaction in membrane, gramicidin-phospholipid, by using $\\sp1$H MASS NMR techniques. The dynamic picture of phospholipid-polypeptide interaction is obtained. Chapter V discusses the application of high resolution $\\sp1$H and $\\sp{13}$C MASS NMR spectroscopy to the study of thylakoid lipids, monogalactosyldiacyglycerol (MGDG), digalactosyldiacylglycerol (DGDG), and sulphoquinovosyldiacylglycerol (SQDG). The chemical shift assignments and the dynamic picture is derived for these thylakoid lipids. Results on studying a variety of phospholipids and sphingomyelin by using $\\sp{13}$C MASS NMR spectroscopy are presented in Chapter VI."","abstract_has_math":true,"creators":["Shan, Xi"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Oldfield, Eric"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-05-07T13:47:15Z","date_published":"2011-05-07T13:47:15Z","updated_at":"2026-07-22T22:25:20Z","subjects":["Chemistry, Physical","Biophysics, General"],"languages":["eng"],"rights":["Copyright 1990 Shan, Xi"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9114408","(UMI)AAI9114408"],"render_values":[{"text":"AAI9114408","href":null,"code":true},{"text":"(UMI)AAI9114408","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/22662","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Oldfield, Eric"]},{"key":"dc:creator","label":"Author","values":["Shan, Xi"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2011-05-07T13:47:15Z","10000-01-01","1990"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Chemistry, Physical","Biophysics, General"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 1990 Shan, Xi"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9114408","(UMI)AAI9114408","http://hdl.handle.net/2142/22662"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["\"This thesis is devoted to the new applications of high resolution $\\sp1$H and $\\sp{13}$C \"\"magic angle sample spinning\"\" (MASS) nuclear magnetic resonance (NMR) techniques to the study of model and biological membranes. Since the resolution of $\\sp1$H and $\\sp{13}$C MASS NMR spectra from multilamella and hexagonal-II phase is the same or even better than that obtained with sonicated liquid-crystalline system, the dynamics of membranes can be studied through measuring linewidth, T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$ relaxation rates for numerous, resolved, single carbon, or individual proton sites by MASS NMR techniques. Chapter II provides a summary of the theoretical background of MASS NMR of model membranes and spin-lattice relaxations of bilayer system. Chapter III discusses the application of high resolution $\\sp1$H MASS NMR to the study of a variety of lipids. The chemical shift assignments, order parameters, and relaxation times (T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$) can be determined for these lipids. Chapter IV reports the study of a typical model system for lipid-protein interaction in membrane, gramicidin-phospholipid, by using $\\sp1$H MASS NMR techniques. The dynamic picture of phospholipid-polypeptide interaction is obtained. Chapter V discusses the application of high resolution $\\sp1$H and $\\sp{13}$C MASS NMR spectroscopy to the study of thylakoid lipids, monogalactosyldiacyglycerol (MGDG), digalactosyldiacylglycerol (DGDG), and sulphoquinovosyldiacylglycerol (SQDG). The chemical shift assignments and the dynamic picture is derived for these thylakoid lipids. Results on studying a variety of phospholipids and sphingomyelin by using $\\sp{13}$C MASS NMR spectroscopy are presented in Chapter VI.\"","Made available in DSpace on 2011-05-07T13:47:15Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9114408.pdf: 5589693 bytes, checksum: 51b396983e0660cf5185e701be5e0ecf (MD5) Previous issue date: 1990","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:59:09Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:27:52-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission","ETDs are only available to UIUC Users without author permission","U of I Only"]},{"key":"dc:title","label":"Title","values":["High-resolution nuclear magnetic resonance studies of lipids and model membranes"]}]}],"canonical_facts":{"dc:contributor":["Oldfield, Eric"],"dc:creator":["Shan, Xi"],"dc:date":["2011-05-07T13:47:15Z","10000-01-01","1990"],"dc:description":["\"This thesis is devoted to the new applications of high resolution $\\sp1$H and $\\sp{13}$C \"\"magic angle sample spinning\"\" (MASS) nuclear magnetic resonance (NMR) techniques to the study of model and biological membranes. Since the resolution of $\\sp1$H and $\\sp{13}$C MASS NMR spectra from multilamella and hexagonal-II phase is the same or even better than that obtained with sonicated liquid-crystalline system, the dynamics of membranes can be studied through measuring linewidth, T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$ relaxation rates for numerous, resolved, single carbon, or individual proton sites by MASS NMR techniques. Chapter II provides a summary of the theoretical background of MASS NMR of model membranes and spin-lattice relaxations of bilayer system. Chapter III discusses the application of high resolution $\\sp1$H MASS NMR to the study of a variety of lipids. The chemical shift assignments, order parameters, and relaxation times (T$\\sb1$, T$\\sb{1\\rho}$, T$\\sb2$) can be determined for these lipids. Chapter IV reports the study of a typical model system for lipid-protein interaction in membrane, gramicidin-phospholipid, by using $\\sp1$H MASS NMR techniques. The dynamic picture of phospholipid-polypeptide interaction is obtained. Chapter V discusses the application of high resolution $\\sp1$H and $\\sp{13}$C MASS NMR spectroscopy to the study of thylakoid lipids, monogalactosyldiacyglycerol (MGDG), digalactosyldiacylglycerol (DGDG), and sulphoquinovosyldiacylglycerol (SQDG). The chemical shift assignments and the dynamic picture is derived for these thylakoid lipids. Results on studying a variety of phospholipids and sphingomyelin by using $\\sp{13}$C MASS NMR spectroscopy are presented in Chapter VI.\"","Made available in DSpace on 2011-05-07T13:47:15Z (GMT). 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