{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/21580"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/21580","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Effects of dietary heated fats and cyclic fatty acid monomers on rat liver enzyme activity","abstract":"The objective of this research was to evaluate the effects of dietary heated fats from a commercial deep-fat frying operation and of cyclic fatty acids (CFA) on rat liver enzyme activity. The fats were partially hydrogenated soybean oil (PHSBO) used 4 days (4-MH) and 7 days (7-DH) for frying foodstuffs. Balanced diets containing these used fats were fed to rats for 10 weeks. In a second experiment, rats were pair-fed diets containing graded doses of 7-DH. In a third, 0.15% CFA diet was fed to animals. In a fourth, rats were pair-fed diet containing the 7-DH treated (T-7DH) with magnesium silicate which removes some polymers from the used oil. All four sets of experiments were conducted with control rats fed non-heated PHSBO (NH) diet. All diets were isocaloric with 15% fat.","abstract_html":"The objective of this research was to evaluate the effects of dietary heated fats from a commercial deep-fat frying operation and of cyclic fatty acids (CFA) on rat liver enzyme activity. The fats were partially hydrogenated soybean oil (PHSBO) used 4 days (4-MH) and 7 days (7-DH) for frying foodstuffs. Balanced diets containing these used fats were fed to rats for 10 weeks. In a second experiment, rats were pair-fed diets containing graded doses of 7-DH. In a third, 0.15% CFA diet was fed to animals. In a fourth, rats were pair-fed diet containing the 7-DH treated (T-7DH) with magnesium silicate which removes some polymers from the used oil. All four sets of experiments were conducted with control rats fed non-heated PHSBO (NH) diet. All diets were isocaloric with 15% fat.","abstract_has_math":false,"creators":["Lamboni, Courdjo"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Nutritional Sciences","degree_department":null,"school":null,"contributors":["Perkins, Edward G."],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-05-07T13:12:52Z","date_published":"2011-05-07T13:12:52Z","updated_at":"2026-07-22T22:25:18Z","subjects":["Chemistry, Biochemistry","Health Sciences, Nutrition"],"languages":["eng"],"rights":["Copyright 1993 Lamboni, Courdjo"],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9411679","(UMI)AAI9411679"],"render_values":[{"text":"AAI9411679","href":null,"code":true},{"text":"(UMI)AAI9411679","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2142/21580","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Perkins, Edward G."]},{"key":"dc:creator","label":"Author","values":["Lamboni, Courdjo"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2011-05-07T13:12:52Z","10000-01-01","1993"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Nutritional Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Chemistry, Biochemistry","Health Sciences, Nutrition"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 1993 Lamboni, Courdjo"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["AAI9411679","(UMI)AAI9411679","http://hdl.handle.net/2142/21580"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The objective of this research was to evaluate the effects of dietary heated fats from a commercial deep-fat frying operation and of cyclic fatty acids (CFA) on rat liver enzyme activity. The fats were partially hydrogenated soybean oil (PHSBO) used 4 days (4-MH) and 7 days (7-DH) for frying foodstuffs. Balanced diets containing these used fats were fed to rats for 10 weeks. In a second experiment, rats were pair-fed diets containing graded doses of 7-DH. In a third, 0.15% CFA diet was fed to animals. In a fourth, rats were pair-fed diet containing the 7-DH treated (T-7DH) with magnesium silicate which removes some polymers from the used oil. All four sets of experiments were conducted with control rats fed non-heated PHSBO (NH) diet. All diets were isocaloric with 15% fat.","Animals fed 7-DH diet either ad libitum or by pair-feeding, showed significant increased contents of cytochromes P$\\sb{450}$ and b$\\sb5$ as well as increased activity of (EC 1.6.2.4) NADPH-cytochrome P$\\sb{450}$ reductase when compared to controls. The 4-MH diet group showed the same trends for cytochromes contents and reductase activity in comparison to controls. Similar results were obtained with CFA diet. The activities of (EC 2.3.1.21) carnitine palmitoyltransferase-I; (EC 1.1.1.42) isocitrate dehydrogenase; were significantly decreased in each case either ad libitum or by pair-feeding in comparison to controls. Significantly depressed activity of (EC 1.1.1.49) glucose 6-phosphate dehydrogenase was also noticed for these animals when compared to NH. Similar results were recorded when fed CFA diet to rats. In addition, liver and microsomal protein were significantly increased when the used oils were fed to rats either ad libitum or by pair-feeding in comparison to NH. Enlarged and fatty livers were noted. Similar results were obtained when fed CFA diet. Liver glycogen was significantly decreased when fed the used oils or CFA diets in comparison to controls. However, when animals were fed T-7DH diet, the activities of the enzymes were significantly improved.","Made available in DSpace on 2011-05-07T13:12:52Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9411679.pdf: 6011968 bytes, checksum: b2d0333749080eb28371e37a88b524b4 (MD5) Previous issue date: 1993","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:51:44Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:23:47-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission","ETDs are only available to UIUC Users without author permission","U of I Only"]},{"key":"dc:title","label":"Title","values":["Effects of dietary heated fats and cyclic fatty acid monomers on rat liver enzyme activity"]}]}],"canonical_facts":{"dc:contributor":["Perkins, Edward G."],"dc:creator":["Lamboni, Courdjo"],"dc:date":["2011-05-07T13:12:52Z","10000-01-01","1993"],"dc:description":["The objective of this research was to evaluate the effects of dietary heated fats from a commercial deep-fat frying operation and of cyclic fatty acids (CFA) on rat liver enzyme activity. The fats were partially hydrogenated soybean oil (PHSBO) used 4 days (4-MH) and 7 days (7-DH) for frying foodstuffs. Balanced diets containing these used fats were fed to rats for 10 weeks. In a second experiment, rats were pair-fed diets containing graded doses of 7-DH. In a third, 0.15% CFA diet was fed to animals. In a fourth, rats were pair-fed diet containing the 7-DH treated (T-7DH) with magnesium silicate which removes some polymers from the used oil. All four sets of experiments were conducted with control rats fed non-heated PHSBO (NH) diet. All diets were isocaloric with 15% fat.","Animals fed 7-DH diet either ad libitum or by pair-feeding, showed significant increased contents of cytochromes P$\\sb{450}$ and b$\\sb5$ as well as increased activity of (EC 1.6.2.4) NADPH-cytochrome P$\\sb{450}$ reductase when compared to controls. The 4-MH diet group showed the same trends for cytochromes contents and reductase activity in comparison to controls. Similar results were obtained with CFA diet. The activities of (EC 2.3.1.21) carnitine palmitoyltransferase-I; (EC 1.1.1.42) isocitrate dehydrogenase; were significantly decreased in each case either ad libitum or by pair-feeding in comparison to controls. Significantly depressed activity of (EC 1.1.1.49) glucose 6-phosphate dehydrogenase was also noticed for these animals when compared to NH. Similar results were recorded when fed CFA diet to rats. In addition, liver and microsomal protein were significantly increased when the used oils were fed to rats either ad libitum or by pair-feeding in comparison to NH. Enlarged and fatty livers were noted. Similar results were obtained when fed CFA diet. Liver glycogen was significantly decreased when fed the used oils or CFA diets in comparison to controls. However, when animals were fed T-7DH diet, the activities of the enzymes were significantly improved.","Made available in DSpace on 2011-05-07T13:12:52Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9411679.pdf: 6011968 bytes, checksum: b2d0333749080eb28371e37a88b524b4 (MD5) Previous issue date: 1993","Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:51:44Z Item is restricted indefinitely.","Restriction data tranferred 2014-07-01T11:23:47-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission","ETDs are only available to UIUC Users without author permission","U of I Only"],"dc:identifier":["AAI9411679","(UMI)AAI9411679","http://hdl.handle.net/2142/21580"],"dc:language":["eng"],"dc:rights":["Copyright 1993 Lamboni, Courdjo"],"dc:subject":["Chemistry, Biochemistry","Health Sciences, Nutrition"],"dc:title":["Effects of dietary heated fats and cyclic fatty acid monomers on rat liver enzyme activity"],"dc:type":["text"],"thesis:degree_discipline":["Nutritional Sciences"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:25:18Z"}