The biosynthesis of brominated tyrosine metabolites by Aplysina fistularis
type: CreativeWork
description: The biosynthesis of brominated tyrosine metabolites by the marine sponge Aplysina fistularis was investigated. ($U$-$\sp{14}$C) -L-Tyrosine, ($U$-$\sp{14}$C) -L-3-bromotyrosine, and ($U$-$\sp{14}$) -3,5-dibromotyrosine were incorporated into both dibromoverongiaquinol and aeroplysinin-1, and (methyl-$\sp{14}$C) methionine was specifically incorporated into the O-methyl group of aeroplysinin-1. (Methyl-$\sp{14}$C) -O-methyltyrosine and (methyl-$\sp{14}$C) -3,5-dibromo-O-methyltyrosine and several putative nitrile precursors were not significantly incorporated into aeroplysinin-1.
abstract: The biosynthesis of brominated tyrosine metabolites by the marine sponge Aplysina fistularis was investigated. ($U$-$\sp{14}$C) -L-Tyrosine, ($U$-$\sp{14}$C) -L-3-bromotyrosine, and ($U$-$\sp{14}$) -3,5-dibromotyrosine were incorporated into both dibromoverongiaquinol and aeroplysinin-1, and (methyl-$\sp{14}$C) methionine was specifically incorporated into the O-methyl group of aeroplysinin-1. (Methyl-$\sp{14}$C) -O-methyltyrosine and (methyl-$\sp{14}$C) -3,5-dibromo-O-methyltyrosine and several putative nitrile precursors were not significantly incorporated into aeroplysinin-1.
author: Carney, John Ray
language: eng
keywords: Chemistry, Organic, Agriculture, Fisheries and Aquaculture
date published: 2011-05-07T12:32:36Z
date modified: 2026-07-22T22:25:15Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/20218