Determination of the trajectory of linker DNA by fluorescence energy transfer distance measurements
We have used fluorescence energy transfer distance measurements to study the trajectory of linker DNA as it enters and exits the histone octamer in a nucleosome core particle. Measurement of the DNA-to-protein distances gives important structural information about the most fundamental level of chromosomal organization, and allows speculation about higher order compaction.
Biology, Molecular, Chemistry, Biochemistry
University of Illinois - Urbana-Champaign
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University of Illinois at Urbana-Champaign