{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/18463"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/18463","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"L1-Adaptive Control for Anesthesia Delivery","abstract":"In this paper, we discuss the first application of recently developed L1-adaptive control methods for the closed-loop control of anesthesia delivery during surgery. Our initial objective, described herein, is to design controllers that are robust to inter-patient variability, such that patients follow a prespecified Bispectral Index (BIS) profile. The controllers are then evaluated on their ability to reject the disturbances effects on the patients’ BIS trajectory that arise during the course of surgery. 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