{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/127358"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/127358","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Hydrothermal synthesis and characterization of carbon dots for enhanced biosensing: A focus on optical properties and DNA interactions","abstract":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01","abstract_html":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01","abstract_has_math":false,"creators":["Morshed, Mehzabin"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Bioengineering","degree_department":null,"school":null,"contributors":["Wang, Xing"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024-11-22","date_published":"2024-11-22","updated_at":"2026-07-22T22:25:03Z","subjects":["Carbon Dots (cds)","Biosensing Applications","Fluorescence Quenching","Optical Properties","Nucleic Acid Interactions","Point-of-care Diagnostics","Real-time Biosensing","Carbon Precursor Optimization","Functionalization Agents","Viral Detection","Dna Structure-dependent Quenching"],"languages":["eng","en"],"rights":["Copyright 2024 Mehzabin Morshed"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/127358","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Wang, Xing"]},{"key":"dc:creator","label":"Author","values":["Morshed, Mehzabin"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2024-11-22","2024-12"]},{"key":"dc:type","label":"Dc Type","values":["text","Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Bioengineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Carbon Dots (cds)","Biosensing Applications","Fluorescence Quenching","Optical Properties","Nucleic Acid Interactions","Point-of-care Diagnostics","Real-time Biosensing","Carbon Precursor Optimization","Functionalization Agents","Viral Detection","Dna Structure-dependent Quenching"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["eng","en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2024 Mehzabin Morshed"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/127358"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01","The student, Mehzabin Morshed, accepted the attached license on 2024-11-21 at 12:52.","The student, Mehzabin Morshed, submitted this Thesis for approval on 2024-11-21 at 13:08.","This Thesis was approved for publication on 2024-11-22 at 09:09.","DSpace SAF Submission Ingestion Package generated from Vireo submission #21364 on 2025-03-28 at 14:43:15","Carbon dots (CDs) have emerged as a promising class of nanomaterials for biosensing applications due to their unique optical properties, including high fluorescence quantum yields, photostability, and biocompatibility. This thesis investigates the synthesis, characterization, and application of CDs in biosensing, focusing on the fluorescence quenching phenomena associated with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The synthesis of CDs was optimized using various carbon precursors and functionalization agents to enhance their fluorescence properties. The interaction dynamics between CDs and nucleic acids were analyzed through concentration, time and structure dependent studies, revealing that these parameters significantly affect fluorescence intensities with quenching effects. The study further explores possible utilization of CDs in real-time biosensing, highlighting their potential for use in point- of-care diagnostics. Findings indicate that the CDs can effectively bind to nucleic acids while maintaining fluorescence, suggesting their versatility in detecting various molecular targets. This research contributes to the understanding of the behavior of CDs in biological systems and underscores their significance as effective fluorescent probes for viral detection."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Hydrothermal synthesis and characterization of carbon dots for enhanced biosensing: A focus on optical properties and DNA interactions"]}]}],"canonical_facts":{"dc:contributor":["Wang, Xing"],"dc:creator":["Morshed, Mehzabin"],"dc:date":["2024-11-22","2024-12"],"dc:description":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-12-01","The student, Mehzabin Morshed, accepted the attached license on 2024-11-21 at 12:52.","The student, Mehzabin Morshed, submitted this Thesis for approval on 2024-11-21 at 13:08.","This Thesis was approved for publication on 2024-11-22 at 09:09.","DSpace SAF Submission Ingestion Package generated from Vireo submission #21364 on 2025-03-28 at 14:43:15","Carbon dots (CDs) have emerged as a promising class of nanomaterials for biosensing applications due to their unique optical properties, including high fluorescence quantum yields, photostability, and biocompatibility. This thesis investigates the synthesis, characterization, and application of CDs in biosensing, focusing on the fluorescence quenching phenomena associated with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The synthesis of CDs was optimized using various carbon precursors and functionalization agents to enhance their fluorescence properties. The interaction dynamics between CDs and nucleic acids were analyzed through concentration, time and structure dependent studies, revealing that these parameters significantly affect fluorescence intensities with quenching effects. The study further explores possible utilization of CDs in real-time biosensing, highlighting their potential for use in point- of-care diagnostics. Findings indicate that the CDs can effectively bind to nucleic acids while maintaining fluorescence, suggesting their versatility in detecting various molecular targets. This research contributes to the understanding of the behavior of CDs in biological systems and underscores their significance as effective fluorescent probes for viral detection."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/127358"],"dc:language":["eng","en"],"dc:rights":["Copyright 2024 Mehzabin Morshed"],"dc:subject":["Carbon Dots (cds)","Biosensing Applications","Fluorescence Quenching","Optical Properties","Nucleic Acid Interactions","Point-of-care Diagnostics","Real-time Biosensing","Carbon Precursor Optimization","Functionalization Agents","Viral Detection","Dna Structure-dependent Quenching"],"dc:title":["Hydrothermal synthesis and characterization of carbon dots for enhanced biosensing: A focus on optical properties and DNA interactions"],"dc:type":["text","Thesis"],"thesis:degree_discipline":["Bioengineering"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["M.S."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:25:03Z"}