{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/124586"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/124586","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"A portable, smartphone-linked, and miniaturized photonic resonator absorption microscope (PRAM MINI) for point-of-care diagnostics","abstract":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01","abstract_html":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01","abstract_has_math":false,"creators":["Khemtonglang, Sydney"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Bioengineering","degree_department":null,"school":null,"contributors":["Cunningham, Brian T"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024-05","date_published":"2024-05","updated_at":"2026-07-22T22:25:02Z","subjects":["Photonic Crystals Biosensor","Absorption Microscopy","Point-of-care Diagnostics"],"languages":["en","eng"],"rights":["Copyright 2024 Sydney Khemtonglang"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/124586","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Cunningham, Brian T"]},{"key":"dc:creator","label":"Author","values":["Khemtonglang, Sydney"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2024-05","2024-05-01"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Bioengineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Photonic Crystals Biosensor","Absorption Microscopy","Point-of-care Diagnostics"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2024 Sydney Khemtonglang"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/124586"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01","The student, Sydney Khemtonglang, accepted the attached license on 2024-04-26 at 12:26.","The student, Sydney Khemtonglang, submitted this Thesis for approval on 2024-04-26 at 12:34.","This Thesis was approved for publication on 2024-05-01 at 16:19.","DSpace SAF Submission Ingestion Package generated from Vireo submission #20658 on 2024-09-16 at 00:44:47","Point-of-care testing (POCT) has revolutionized healthcare with its rapid, accurate, and all-in-one diagnostic capabilities. In this work, we report the development and validation of the miniaturized Photonic Resonator Absorption Microscope (PRAM Mini), integrated wirelessly with a smartphone application. PRAM Mini harnesses the unique optical coupling of photonic crystal (PC) guided-mode resonance and gold nanoparticle (AuNP) localized surface plasmon resonance to achieve a significant reduction in reflected PC intensity caused by the localized quenching of the AuNP. As an initial demonstration, PRAM Mini effectively detects SARS-CoV-2 antibodies in clinical samples using a blocking biosensor assay. PRAM Mini offers a compact and cost-effective solution for point-of-care diagnostics with text-book-sized dimensions of 23 cm × 21 cm × 10 cm and a total cost of $2,111.65. Its digital resolution quantification features and smartphone-linked functionality enhance accessibility and usability in diverse healthcare settings. The PRAM Mini is a promising tool for addressing the increasing demand for portable and efficient diagnostic solutions, contributing significantly to improved patient care and healthcare system efficiency."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["A portable, smartphone-linked, and miniaturized photonic resonator absorption microscope (PRAM MINI) for point-of-care diagnostics"]}]}],"canonical_facts":{"dc:contributor":["Cunningham, Brian T"],"dc:creator":["Khemtonglang, Sydney"],"dc:date":["2024-05","2024-05-01"],"dc:description":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2026-05-01","The student, Sydney Khemtonglang, accepted the attached license on 2024-04-26 at 12:26.","The student, Sydney Khemtonglang, submitted this Thesis for approval on 2024-04-26 at 12:34.","This Thesis was approved for publication on 2024-05-01 at 16:19.","DSpace SAF Submission Ingestion Package generated from Vireo submission #20658 on 2024-09-16 at 00:44:47","Point-of-care testing (POCT) has revolutionized healthcare with its rapid, accurate, and all-in-one diagnostic capabilities. In this work, we report the development and validation of the miniaturized Photonic Resonator Absorption Microscope (PRAM Mini), integrated wirelessly with a smartphone application. PRAM Mini harnesses the unique optical coupling of photonic crystal (PC) guided-mode resonance and gold nanoparticle (AuNP) localized surface plasmon resonance to achieve a significant reduction in reflected PC intensity caused by the localized quenching of the AuNP. As an initial demonstration, PRAM Mini effectively detects SARS-CoV-2 antibodies in clinical samples using a blocking biosensor assay. PRAM Mini offers a compact and cost-effective solution for point-of-care diagnostics with text-book-sized dimensions of 23 cm × 21 cm × 10 cm and a total cost of $2,111.65. Its digital resolution quantification features and smartphone-linked functionality enhance accessibility and usability in diverse healthcare settings. The PRAM Mini is a promising tool for addressing the increasing demand for portable and efficient diagnostic solutions, contributing significantly to improved patient care and healthcare system efficiency."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/124586"],"dc:language":["en","eng"],"dc:rights":["Copyright 2024 Sydney Khemtonglang"],"dc:subject":["Photonic Crystals Biosensor","Absorption Microscopy","Point-of-care Diagnostics"],"dc:title":["A portable, smartphone-linked, and miniaturized photonic resonator absorption microscope (PRAM MINI) for point-of-care diagnostics"],"dc:type":["text"],"thesis:degree_discipline":["Bioengineering"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["M.S."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:25:02Z"}