{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/124360"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/124360","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Defining the relationship between basal myofibrillar protein synthesis and resting metabolic rate","abstract":"Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms","abstract_html":"Submission original under an indefinite embargo labeled &#x27;Open Access&#x27;. The submission was exported from vireo on 2024-09-16 without embargo terms","abstract_has_math":false,"creators":["Bein, David William"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Kinesiology","degree_department":null,"school":null,"contributors":["Burd, Nicholas A"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2024,"date_issued":"2024-05","date_published":"2024-05","updated_at":"2026-07-22T22:25:00Z","subjects":["Skeletal Muscle Mass","Weight Management","Muscle Protein Turnover","Energy Expenditure","Fractional Synthetic Rate"],"languages":["en","eng"],"rights":["Copyright 2024 David Bein"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/124360","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Burd, Nicholas A"]},{"key":"dc:creator","label":"Author","values":["Bein, David William"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2024-05","2024-04-29"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Kinesiology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Skeletal Muscle Mass","Weight Management","Muscle Protein Turnover","Energy Expenditure","Fractional Synthetic Rate"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2024 David Bein"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/124360"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms","The student, David Bein, accepted the attached license on 2024-04-22 at 12:33.","The student, David Bein, submitted this Thesis for approval on 2024-04-22 at 12:45.","This Thesis was approved for publication on 2024-04-29 at 12:50.","DSpace SAF Submission Ingestion Package generated from Vireo submission #20539 on 2024-09-16 at 00:35:45","Obesity is a widespread public health crisis with a myriad of contributing factors such as lack of adherence to healthy eating patterns, reduced habitual physical activity, and increased sedentary behavior. While much time has been spent examining the active components that comprise an individual’s net energy balance, less focus has been given towards the passive, basal contributions. Chief among those is resting metabolic rate. The impact of skeletal muscle quantity and quality on resting metabolic rate has been well documented, but the potential influence of muscle protein turnover rates is less well understood. Chronic maintenance of a positive net energy balance (surplus) may lead to obesity, resulting in elevated disease risks. Resting metabolic rate (RMR) is the greatest contributor of total daily energy expenditure (TDEE) and therefore has an important role in weight maintenance. Indeed, increasing habitual physical activity and incorporation of targeted exercise strategies into a life routine can help counterbalance an increased energy surplus in an acute manner, with this relationship being well documented. The maintenance (or growth) of skeletal muscle tissue may also help to passively counteract a chronic energetic surplus due to the significant contribution of skeletal muscle mass, driven by the amount and quality, particularly when compared to other factors such as age. The importance of mixed muscle protein turnover on skeletal muscle quantity and quality, as well as RMR is well understood, but the contribution of specific protein pools or fractions (e.g., myofibrillar protein pool) within the muscle is less well understood. As such, the purpose of this thesis was to fill this research gap by examining the relationship between myofibrillar protein synthesis and RMR in healthy adults. We demonstrated that the specific energetic contribution of basal myofibrillar protein synthesis is insufficient to modulate RMR in healthy adults."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Defining the relationship between basal myofibrillar protein synthesis and resting metabolic rate"]}]}],"canonical_facts":{"dc:contributor":["Burd, Nicholas A"],"dc:creator":["Bein, David William"],"dc:date":["2024-05","2024-04-29"],"dc:description":["Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms","The student, David Bein, accepted the attached license on 2024-04-22 at 12:33.","The student, David Bein, submitted this Thesis for approval on 2024-04-22 at 12:45.","This Thesis was approved for publication on 2024-04-29 at 12:50.","DSpace SAF Submission Ingestion Package generated from Vireo submission #20539 on 2024-09-16 at 00:35:45","Obesity is a widespread public health crisis with a myriad of contributing factors such as lack of adherence to healthy eating patterns, reduced habitual physical activity, and increased sedentary behavior. While much time has been spent examining the active components that comprise an individual’s net energy balance, less focus has been given towards the passive, basal contributions. Chief among those is resting metabolic rate. The impact of skeletal muscle quantity and quality on resting metabolic rate has been well documented, but the potential influence of muscle protein turnover rates is less well understood. Chronic maintenance of a positive net energy balance (surplus) may lead to obesity, resulting in elevated disease risks. Resting metabolic rate (RMR) is the greatest contributor of total daily energy expenditure (TDEE) and therefore has an important role in weight maintenance. Indeed, increasing habitual physical activity and incorporation of targeted exercise strategies into a life routine can help counterbalance an increased energy surplus in an acute manner, with this relationship being well documented. The maintenance (or growth) of skeletal muscle tissue may also help to passively counteract a chronic energetic surplus due to the significant contribution of skeletal muscle mass, driven by the amount and quality, particularly when compared to other factors such as age. The importance of mixed muscle protein turnover on skeletal muscle quantity and quality, as well as RMR is well understood, but the contribution of specific protein pools or fractions (e.g., myofibrillar protein pool) within the muscle is less well understood. As such, the purpose of this thesis was to fill this research gap by examining the relationship between myofibrillar protein synthesis and RMR in healthy adults. We demonstrated that the specific energetic contribution of basal myofibrillar protein synthesis is insufficient to modulate RMR in healthy adults."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/124360"],"dc:language":["en","eng"],"dc:rights":["Copyright 2024 David Bein"],"dc:subject":["Skeletal Muscle Mass","Weight Management","Muscle Protein Turnover","Energy Expenditure","Fractional Synthetic Rate"],"dc:title":["Defining the relationship between basal myofibrillar protein synthesis and resting metabolic rate"],"dc:type":["text"],"thesis:degree_discipline":["Kinesiology"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["M.S."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:25:00Z"}