{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/122189"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/122189","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Environmental modulators of algae-bacteria interactions at scale","abstract":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01","abstract_html":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01","abstract_has_math":false,"creators":["Gopalakrishnappa, Chandana"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Physics","degree_department":null,"school":null,"contributors":["Kuehn, Seppe","Golding, Ido","Heath, Katy","Maslov, Sergei"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2023,"date_issued":"2023-12","date_published":"2023-12","updated_at":"2026-07-22T22:25:00Z","subjects":["Droplet Microfluidics","High-throughput","Microbial Ecology","Phototroph-heterotroph Interactions","High Dimensional Environments","Statistical Modeling"],"languages":["en","eng"],"rights":["Copyright 2023 Chandana Gopalakrishnappa"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/122189","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Kuehn, Seppe","Golding, Ido","Heath, Katy","Maslov, Sergei"]},{"key":"dc:creator","label":"Author","values":["Gopalakrishnappa, Chandana"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2023-12","2023-08-07"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Physics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Droplet Microfluidics","High-throughput","Microbial Ecology","Phototroph-heterotroph Interactions","High Dimensional Environments","Statistical Modeling"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2023 Chandana Gopalakrishnappa"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/122189"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01","The student, Chandana Gopalakrishnappa, accepted the attached license on 2023-07-03 at 15:21.","The student, Chandana Gopalakrishnappa, submitted this Dissertation for approval on 2023-07-03 at 23:51.","This Dissertation was approved for publication on 2023-08-07 at 11:47.","DSpace SAF Submission Ingestion Package generated from Vireo submission #19504 on 2024-03-01 at 13:47:33","Photosynthetic microbes associated with non-photosynthetic, heterotrophic bacteria play a crucial role in global primary production, nutrient cycling, and industrial processes. Understanding these phototroph-heterotroph associations is therefore important but remains challenging because they reside in chemically complex aquatic and terrestrial environments. We do not understand how the myriad of environmental parameters, from nutrient availability to pH, impact interactions between phototrophs and their heterotrophic partners. Here, we leverage a massively parallel droplet microfluidic platform that enables us to interrogate algae-bacteria interactions in >100,000 communities across ~525 environmental conditions with varying pH, phosphorous availability. carbon availability and carbon source identity. By developing a statistical framework to dissect interactions in this complex dataset, we reveal that the dependence of algae-bacteria interactions on nutrient availability is strongly modulated by pH and buffering capacity. Furthermore, we show that the chemical identity of the available organic carbon source controls how pH, buffering capacity, and nutrient availability modulate algae-bacteria interactions. By leveraging a high-throughput platform, our study reveals the previously underappreciated role of pH in modulating phototroph-heterotroph interactions."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Environmental modulators of algae-bacteria interactions at scale"]}]}],"canonical_facts":{"dc:contributor":["Kuehn, Seppe","Golding, Ido","Heath, Katy","Maslov, Sergei"],"dc:creator":["Gopalakrishnappa, Chandana"],"dc:date":["2023-12","2023-08-07"],"dc:description":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01","The student, Chandana Gopalakrishnappa, accepted the attached license on 2023-07-03 at 15:21.","The student, Chandana Gopalakrishnappa, submitted this Dissertation for approval on 2023-07-03 at 23:51.","This Dissertation was approved for publication on 2023-08-07 at 11:47.","DSpace SAF Submission Ingestion Package generated from Vireo submission #19504 on 2024-03-01 at 13:47:33","Photosynthetic microbes associated with non-photosynthetic, heterotrophic bacteria play a crucial role in global primary production, nutrient cycling, and industrial processes. Understanding these phototroph-heterotroph associations is therefore important but remains challenging because they reside in chemically complex aquatic and terrestrial environments. We do not understand how the myriad of environmental parameters, from nutrient availability to pH, impact interactions between phototrophs and their heterotrophic partners. Here, we leverage a massively parallel droplet microfluidic platform that enables us to interrogate algae-bacteria interactions in >100,000 communities across ~525 environmental conditions with varying pH, phosphorous availability. carbon availability and carbon source identity. By developing a statistical framework to dissect interactions in this complex dataset, we reveal that the dependence of algae-bacteria interactions on nutrient availability is strongly modulated by pH and buffering capacity. Furthermore, we show that the chemical identity of the available organic carbon source controls how pH, buffering capacity, and nutrient availability modulate algae-bacteria interactions. By leveraging a high-throughput platform, our study reveals the previously underappreciated role of pH in modulating phototroph-heterotroph interactions."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/122189"],"dc:language":["en","eng"],"dc:rights":["Copyright 2023 Chandana Gopalakrishnappa"],"dc:subject":["Droplet Microfluidics","High-throughput","Microbial Ecology","Phototroph-heterotroph Interactions","High Dimensional Environments","Statistical Modeling"],"dc:title":["Environmental modulators of algae-bacteria interactions at scale"],"dc:type":["text"],"thesis:degree_discipline":["Physics"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:25:00Z"}