{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/121212"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/121212","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Protein corona formation and analysis on colloidal inorganic nanoparticles","abstract":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01","abstract_html":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01","abstract_has_math":false,"creators":["Hoang, Khoi Nguyen Le"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":["Murphy, Catherine J","Chan, Jefferson","Huang, Pinshane","Wheeler, Korin E"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2023,"date_issued":"2023-08","date_published":"2023-08","updated_at":"2026-07-22T22:24:57Z","subjects":["Protein Corona","Inorganic Nanoparticles"],"languages":["en","eng"],"rights":["Copyright 2023 Khoi Nguyen Hoang"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/121212","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Murphy, Catherine J","Chan, Jefferson","Huang, Pinshane","Wheeler, Korin E"]},{"key":"dc:creator","label":"Author","values":["Hoang, Khoi Nguyen Le"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2023-08","2023-07-10"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Protein Corona","Inorganic Nanoparticles"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2023 Khoi Nguyen Hoang"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/121212"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01","The student, Khoi Nguyen Hoang, accepted the attached license on 2023-06-30 at 22:39.","The student, Khoi Nguyen Hoang, submitted this Dissertation for approval on 2023-06-30 at 22:40.","This Dissertation was approved for publication on 2023-07-10 at 16:27.","DSpace SAF Submission Ingestion Package generated from Vireo submission #19493 on 2023-12-04 at 17:30:36","Due to their unique physiochemical properties exhibited at the nanoscale, nanoparticles are being increasingly utilized to better human experience in many different applications, including energy, transportation, information technology, medicine, food safety, and consumer products. The widespread interest and utilization of their tunable properties will likely result in the release of nanoparticles into the environment. Additional molecular understanding of the protein corona is needed to prevent negative environmental and health impacts and to develop sustainable nanotechnology. In this work, Chapter 1 introduces the field of nanotechnology and colloidal inorganic nanoparticles with a focus on gold and iron oxide nanoparticles as well as the concepts of the nanobio interface and the importance of the protein corona. Chapter 2 details the importance of isolation method on the protein corona composition when analyzing the protein corona upon incubation with gold-coated iron oxide nanoparticles. Chapter 3 describes the consequences of protein disulfide isomerase, a redox-active protein, upon exposure to gold nanoparticles using limited proteolytic mass spectrometry analysis. In Chapter 4, the focus is shifted to understanding the effects of nanoparticle surface functionalization on the protein corona formation in plants."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Protein corona formation and analysis on colloidal inorganic nanoparticles"]}]}],"canonical_facts":{"dc:contributor":["Murphy, Catherine J","Chan, Jefferson","Huang, Pinshane","Wheeler, Korin E"],"dc:creator":["Hoang, Khoi Nguyen Le"],"dc:date":["2023-08","2023-07-10"],"dc:description":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01","The student, Khoi Nguyen Hoang, accepted the attached license on 2023-06-30 at 22:39.","The student, Khoi Nguyen Hoang, submitted this Dissertation for approval on 2023-06-30 at 22:40.","This Dissertation was approved for publication on 2023-07-10 at 16:27.","DSpace SAF Submission Ingestion Package generated from Vireo submission #19493 on 2023-12-04 at 17:30:36","Due to their unique physiochemical properties exhibited at the nanoscale, nanoparticles are being increasingly utilized to better human experience in many different applications, including energy, transportation, information technology, medicine, food safety, and consumer products. The widespread interest and utilization of their tunable properties will likely result in the release of nanoparticles into the environment. Additional molecular understanding of the protein corona is needed to prevent negative environmental and health impacts and to develop sustainable nanotechnology. In this work, Chapter 1 introduces the field of nanotechnology and colloidal inorganic nanoparticles with a focus on gold and iron oxide nanoparticles as well as the concepts of the nanobio interface and the importance of the protein corona. Chapter 2 details the importance of isolation method on the protein corona composition when analyzing the protein corona upon incubation with gold-coated iron oxide nanoparticles. Chapter 3 describes the consequences of protein disulfide isomerase, a redox-active protein, upon exposure to gold nanoparticles using limited proteolytic mass spectrometry analysis. In Chapter 4, the focus is shifted to understanding the effects of nanoparticle surface functionalization on the protein corona formation in plants."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/121212"],"dc:language":["en","eng"],"dc:rights":["Copyright 2023 Khoi Nguyen Hoang"],"dc:subject":["Protein Corona","Inorganic Nanoparticles"],"dc:title":["Protein corona formation and analysis on colloidal inorganic nanoparticles"],"dc:type":["text"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:24:57Z"}