{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/116165"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/116165","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Joint-optimization of the x-ray source voltage, beam filtration and detection angle for a full-ring benchtop x-ray fluorescence computed tomography (XFCT) image system","abstract":"Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms","abstract_html":"Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms","abstract_has_math":false,"creators":["Nie, Xingchen"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Nuclear, Plasma, Radiolgc Engr","degree_department":null,"school":null,"contributors":["Meng, Lingjian","Di Fulvio, Angela"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2022,"date_issued":"2022-08","date_published":"2022-08","updated_at":"2026-07-22T22:24:55Z","subjects":["X-Ray","XFCT","Fluorescence","signal-to-noise"],"languages":["en","eng"],"rights":["Copyright 2022 Xingchen Nie"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://hdl.handle.net/2142/116165","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Meng, Lingjian","Di Fulvio, Angela"]},{"key":"dc:creator","label":"Author","values":["Nie, Xingchen"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2022-08","2022-07-08"]},{"key":"dc:type","label":"Dc Type","values":["text","Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Nuclear, Plasma, Radiolgc Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["X-Ray","XFCT","Fluorescence","signal-to-noise"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2022 Xingchen Nie"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://hdl.handle.net/2142/116165"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms","The student, Xingchen Nie, accepted the attached license on 2022-06-23 at 14:54.","The student, Xingchen Nie, submitted this Thesis for approval on 2022-06-23 at 15:40.","This Thesis was approved for publication on 2022-07-08 at 13:57.","DSpace SAF Submission Ingestion Package generated from Vireo submission #18098 on 2022-11-15 at 17:37:40","In this thesis, we present a combined theoretical and Monte Carlo study to optimize the design of a full-ring desktop X-Ray Fluorescence Computed Tomography (XFCT) system based on ultrahigh energy resolution CdTe detectors and a pencil-beam-irradiation/multiple-slit camera (PB/MS) geometry. In this study, we have specifically focused on a joint-optimization of X-ray source voltage, beam filtering and signal-collection angle for improving the signal-to-noise ratio attainable with the imaging setup. Given a large number of possible combinations of these design parameters, we have developed an analytical approach that could be used to rapidly evaluate the intrinsic signal-to-noise ratio (SNR) that measures the fluorescence signal, Compton scattering noise, and Rayleigh scattering noise generated under a simplified X-ray irradiation and data collection geometry. We have used this method to search through a large number (a total of 4800 in this study) of different combinations of system parameters, such as X-ray tube voltage, filter material, thickness, angle of detection, etc., to identify the potential optimum choice of system parameters. The study shows the following two conclusions, (1) If the dose is the primary concern, the value of the SNR improved with an increased filter thickness and a large back-ward signal collection angle, (2) Given the X-ray tube maximum power, the maximum tube voltage with a signal collection angle of 80-100 degrees can reach the optimum SNR. These results were further validated through Monte Carlo studies with more realistic imaging geometries."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Joint-optimization of the x-ray source voltage, beam filtration and detection angle for a full-ring benchtop x-ray fluorescence computed tomography (XFCT) image system"]}]}],"canonical_facts":{"dc:contributor":["Meng, Lingjian","Di Fulvio, Angela"],"dc:creator":["Nie, Xingchen"],"dc:date":["2022-08","2022-07-08"],"dc:description":["Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-15 without embargo terms","The student, Xingchen Nie, accepted the attached license on 2022-06-23 at 14:54.","The student, Xingchen Nie, submitted this Thesis for approval on 2022-06-23 at 15:40.","This Thesis was approved for publication on 2022-07-08 at 13:57.","DSpace SAF Submission Ingestion Package generated from Vireo submission #18098 on 2022-11-15 at 17:37:40","In this thesis, we present a combined theoretical and Monte Carlo study to optimize the design of a full-ring desktop X-Ray Fluorescence Computed Tomography (XFCT) system based on ultrahigh energy resolution CdTe detectors and a pencil-beam-irradiation/multiple-slit camera (PB/MS) geometry. In this study, we have specifically focused on a joint-optimization of X-ray source voltage, beam filtering and signal-collection angle for improving the signal-to-noise ratio attainable with the imaging setup. Given a large number of possible combinations of these design parameters, we have developed an analytical approach that could be used to rapidly evaluate the intrinsic signal-to-noise ratio (SNR) that measures the fluorescence signal, Compton scattering noise, and Rayleigh scattering noise generated under a simplified X-ray irradiation and data collection geometry. We have used this method to search through a large number (a total of 4800 in this study) of different combinations of system parameters, such as X-ray tube voltage, filter material, thickness, angle of detection, etc., to identify the potential optimum choice of system parameters. The study shows the following two conclusions, (1) If the dose is the primary concern, the value of the SNR improved with an increased filter thickness and a large back-ward signal collection angle, (2) Given the X-ray tube maximum power, the maximum tube voltage with a signal collection angle of 80-100 degrees can reach the optimum SNR. These results were further validated through Monte Carlo studies with more realistic imaging geometries."],"dc:format":["application/pdf"],"dc:identifier":["https://hdl.handle.net/2142/116165"],"dc:language":["en","eng"],"dc:rights":["Copyright 2022 Xingchen Nie"],"dc:subject":["X-Ray","XFCT","Fluorescence","signal-to-noise"],"dc:title":["Joint-optimization of the x-ray source voltage, beam filtration and detection angle for a full-ring benchtop x-ray fluorescence computed tomography (XFCT) image system"],"dc:type":["text","Thesis"],"thesis:degree_discipline":["Nuclear, Plasma, Radiolgc Engr"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["M.S."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:24:55Z"}