{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/114052"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/114052","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Atomically thin solid-state nanopore field-effect transistors for single-molecule sensing","abstract":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01","abstract_html":"Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01","abstract_has_math":false,"creators":["Athreya, Nagendra Bala Murali"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Electrical & Computer Engr","degree_department":null,"school":null,"contributors":["Leburton, Jean-Pierre","Radenovic, Aleksandra","Milenkovic, Olgica","Vlasov, Yurii"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2022,"date_issued":"2022-04-29T21:58:19Z","date_published":"2022-04-29T21:58:19Z","updated_at":"2026-07-22T22:24:54Z","subjects":["Engineering"],"languages":["en","eng"],"rights":["Copyright 2021 Nagendra Bala Murali Athreya"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/114052","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Leburton, Jean-Pierre","Radenovic, Aleksandra","Milenkovic, Olgica","Vlasov, Yurii"]},{"key":"dc:creator","label":"Author","values":["Athreya, Nagendra Bala Murali"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2022-04-29T21:58:19Z","2024-04-29T21:58:46Z","2021-12","2021-11-03"]},{"key":"dc:type","label":"Dc Type","values":["text","Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical & Computer Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Engineering"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2021 Nagendra Bala Murali Athreya"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/114052"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01","The student, Nagendra Bala Murali Athreya, accepted the attached license on 2021-10-29 at 15:20.","The student, Nagendra Bala Murali Athreya, submitted this Dissertation for approval on 2021-10-29 at 15:35.","This Dissertation was approved for publication on 2021-11-03 at 14:21.","DSpace SAF Submission Ingestion Package generated from Vireo submission #17179 on 2022-04-29 at 16:09:22","Made available in DSpace on 2022-04-29T21:58:19Z (GMT). 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In this context, two-dimensional solid-state materials such as graphene and MoS2 have gained much interest for ultra-fast and reliable sensing because of their atom size thickness that anticipates excellent spatial resolution and their electrical responsivity that enables sensing in-plane electron current modulated by the molecule translocating through the pore, simultaneously with ionic blockade current. This dissertation focuses on the development and implementation of a comprehensive computational model for atomically thin solid-state nanopore FETs applied toward single bio-molecule sensing. The developed software pipeline combines all-atom molecular dynamics simulations with electron transport modeling in semiconducting 2D membranes and statistical signal processing to analyze the detailed interaction between biomolecules and solid-state nanopore membranes. Various scalable FET architectures are explored in efforts to improve the sensor signal quality and bio-molecule detection capabilities. The validation of the device designs and methodology is illustrated with some of the important biomedical applications such as DNA sensing, epigenetic detection of DNA methylation, and identification of single-stranded breaks in dsDNA."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Atomically thin solid-state nanopore field-effect transistors for single-molecule sensing"]}]}],"canonical_facts":{"dc:contributor":["Leburton, Jean-Pierre","Radenovic, Aleksandra","Milenkovic, Olgica","Vlasov, Yurii"],"dc:creator":["Athreya, Nagendra Bala Murali"],"dc:date":["2022-04-29T21:58:19Z","2024-04-29T21:58:46Z","2021-12","2021-11-03"],"dc:description":["Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2023-12-01","The student, Nagendra Bala Murali Athreya, accepted the attached license on 2021-10-29 at 15:20.","The student, Nagendra Bala Murali Athreya, submitted this Dissertation for approval on 2021-10-29 at 15:35.","This Dissertation was approved for publication on 2021-11-03 at 14:21.","DSpace SAF Submission Ingestion Package generated from Vireo submission #17179 on 2022-04-29 at 16:09:22","Made available in DSpace on 2022-04-29T21:58:19Z (GMT). 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In this context, two-dimensional solid-state materials such as graphene and MoS2 have gained much interest for ultra-fast and reliable sensing because of their atom size thickness that anticipates excellent spatial resolution and their electrical responsivity that enables sensing in-plane electron current modulated by the molecule translocating through the pore, simultaneously with ionic blockade current. This dissertation focuses on the development and implementation of a comprehensive computational model for atomically thin solid-state nanopore FETs applied toward single bio-molecule sensing. The developed software pipeline combines all-atom molecular dynamics simulations with electron transport modeling in semiconducting 2D membranes and statistical signal processing to analyze the detailed interaction between biomolecules and solid-state nanopore membranes. Various scalable FET architectures are explored in efforts to improve the sensor signal quality and bio-molecule detection capabilities. The validation of the device designs and methodology is illustrated with some of the important biomedical applications such as DNA sensing, epigenetic detection of DNA methylation, and identification of single-stranded breaks in dsDNA."],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/2142/114052"],"dc:language":["en","eng"],"dc:rights":["Copyright 2021 Nagendra Bala Murali Athreya"],"dc:subject":["Engineering"],"dc:title":["Atomically thin solid-state nanopore field-effect transistors for single-molecule sensing"],"dc:type":["text","Thesis"],"thesis:degree_discipline":["Electrical & Computer Engr"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:24:54Z"}