{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/113955"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/113955","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Optical parametric amplification of optical imaging signals","abstract":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-12-01","abstract_html":"Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-12-01","abstract_has_math":false,"creators":["Sun, Yi"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Electrical & Computer Engr","degree_department":null,"school":null,"contributors":["Boppart, Stephen A","Gao, Liang","Dragic, Peter","Popescu, Gabriel"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2022,"date_issued":"2022-04-29T21:42:54Z","date_published":"2022-04-29T21:42:54Z","updated_at":"2026-07-22T22:24:53Z","subjects":["Engineering"],"languages":["en","eng"],"rights":["Copyright 2021 Yi Sun"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/113955","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Boppart, Stephen A","Gao, Liang","Dragic, Peter","Popescu, Gabriel"]},{"key":"dc:creator","label":"Author","values":["Sun, Yi"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2022-04-29T21:42:54Z","2024-04-29T21:47:53Z","2021-12","2021-10-14"]},{"key":"dc:type","label":"Dc Type","values":["text","Thesis"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Electrical & Computer Engr"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Engineering"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en","eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2021 Yi Sun"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/113955"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-12-01","The student, Yi Sun, accepted the attached license on 2021-10-06 at 03:21.","The student, Yi Sun, submitted this Dissertation for approval on 2021-10-06 at 03:28.","This Dissertation was approved for publication on 2021-10-14 at 16:55.","DSpace SAF Submission Ingestion Package generated from Vireo submission #17150 on 2022-04-06 at 17:16:38","Made available in DSpace on 2022-04-29T21:42:54Z (GMT). No. of bitstreams: 2 SUN-DISSERTATION-2021.pdf: 3946134 bytes, checksum: 9765036faabc71d430bf33008602733a (MD5) LICENSE.txt: 4203 bytes, checksum: 4d0f42520e5cd653e97e79c942322e8c (MD5) Previous issue date: 2021-10-14","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:43:01Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:44:44Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:46:25Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:47:53Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","U of I Only","Optical imaging is an essential approach to study the characteristics of samples in different fields of study, particularly in biomedical research. Various imaging techniques like optical coherence tomography and nonlinear optical microscopy provide the structural and molecular contrasts of biomedical samples. The detection of these optical imaging signals require special techniques to preserve the signal integrity and block the background noise. In particular, the optical imaging signal coming from deep tissue or nonlinear optical processes is too weak for regular photodiode-based detectors to effectively collect. Various optical detection methods have been invented, such as interferometry in optical coherence tomography (OCT) and secondary electron emission in photomultiplier tubes (PMTs). However, interferometry has only been used in linear reflectance imaging signal detection, while the PMT is severely affected by the background light noise since the secondary electron emission indiscriminately amplifies all the photoelectrons. In this thesis work, I proposed and realized the use of the optical parametric amplification process to amplify the imaging signals. As a nonlinear optical process, the optical parametric amplification (OPA) process heavily relies on the light coherence, and this characteristic of OPA completely rules out the incoherent background room light. In addition, the theoretical detection limit of OPA reaches and even surpasses the quantum mechanical shot noise limit, and potentially performs better than PMTs. For the detection of the microscopic imaging signal under ambient room light, the OPA utilized in this study achieved a similar signal gain and detection limit compared to the results of PMTs under extremely dark conditions. This superior performance of OPA detection may potentially replace the predominantly used PMTs in microscopy imaging"]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Optical parametric amplification of optical imaging signals"]}]}],"canonical_facts":{"dc:contributor":["Boppart, Stephen A","Gao, Liang","Dragic, Peter","Popescu, Gabriel"],"dc:creator":["Sun, Yi"],"dc:date":["2022-04-29T21:42:54Z","2024-04-29T21:47:53Z","2021-12","2021-10-14"],"dc:description":["Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2023-12-01","The student, Yi Sun, accepted the attached license on 2021-10-06 at 03:21.","The student, Yi Sun, submitted this Dissertation for approval on 2021-10-06 at 03:28.","This Dissertation was approved for publication on 2021-10-14 at 16:55.","DSpace SAF Submission Ingestion Package generated from Vireo submission #17150 on 2022-04-06 at 17:16:38","Made available in DSpace on 2022-04-29T21:42:54Z (GMT). No. of bitstreams: 2 SUN-DISSERTATION-2021.pdf: 3946134 bytes, checksum: 9765036faabc71d430bf33008602733a (MD5) LICENSE.txt: 4203 bytes, checksum: 4d0f42520e5cd653e97e79c942322e8c (MD5) Previous issue date: 2021-10-14","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:43:01Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:44:44Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:46:25Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Embargo set by: Seth Robbins for item 123317 Lift date: 2024-04-29T21:47:53Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system","U of I Only","Optical imaging is an essential approach to study the characteristics of samples in different fields of study, particularly in biomedical research. Various imaging techniques like optical coherence tomography and nonlinear optical microscopy provide the structural and molecular contrasts of biomedical samples. The detection of these optical imaging signals require special techniques to preserve the signal integrity and block the background noise. In particular, the optical imaging signal coming from deep tissue or nonlinear optical processes is too weak for regular photodiode-based detectors to effectively collect. Various optical detection methods have been invented, such as interferometry in optical coherence tomography (OCT) and secondary electron emission in photomultiplier tubes (PMTs). However, interferometry has only been used in linear reflectance imaging signal detection, while the PMT is severely affected by the background light noise since the secondary electron emission indiscriminately amplifies all the photoelectrons. In this thesis work, I proposed and realized the use of the optical parametric amplification process to amplify the imaging signals. As a nonlinear optical process, the optical parametric amplification (OPA) process heavily relies on the light coherence, and this characteristic of OPA completely rules out the incoherent background room light. In addition, the theoretical detection limit of OPA reaches and even surpasses the quantum mechanical shot noise limit, and potentially performs better than PMTs. For the detection of the microscopic imaging signal under ambient room light, the OPA utilized in this study achieved a similar signal gain and detection limit compared to the results of PMTs under extremely dark conditions. This superior performance of OPA detection may potentially replace the predominantly used PMTs in microscopy imaging"],"dc:format":["application/pdf"],"dc:identifier":["http://hdl.handle.net/2142/113955"],"dc:language":["en","eng"],"dc:rights":["Copyright 2021 Yi Sun"],"dc:subject":["Engineering"],"dc:title":["Optical parametric amplification of optical imaging signals"],"dc:type":["text","Thesis"],"thesis:degree_discipline":["Electrical & Computer Engr"],"thesis:degree_level":["Dissertation"],"thesis:degree_name":["Ph.D."],"thesis:institution_name":["University of Illinois at Urbana-Champaign"]},"updated_at":"2026-07-22T22:24:53Z"}