Effects of yeast products on immune response and intestinal health of dogs and mice
type: CreativeWork
description: With growing pet populations and the trend of pet humanization, the demand for functional ingredients that provide health benefits beyond basic nutrition has continued to increase in the pet food industry. Yeast products may serve as functional ingredients due to their potential health benefits as shown in livestock and rodents. Previous studies in dogs demonstrated some positive results of yeast supplementation in terms of modulating a few specific fecal microbiota and immune cell numbers, but little is known regarding the effects of yeast products on immune cell responsiveness, fecal microbiota profiles, and gut integrity. Herein, we aimed to test yeast products and hypothesized that they may provide health benefits and serve as functional ingredients in dog diets by enhancing immune response and promoting intestinal health. The first aim was to evaluate the effects of a Saccharomyces cerevisiae fermentation product (SCFP) on apparent total tract digestibility (ATTD), fecal characteristics, fecal fermentative end-products, fecal microbiota, immune cell populations, immune cell responsiveness, and diet palatability of healthy adult dogs. Twelve healthy adult female beagles (mean age = 3.3 ± 0.8 yr; mean BW = 10.3 ± 0.68 kg) were fed the same diet, but supplemented with 3 levels of yeast fermentation products (125, 250 or 500 mg/d) or a placebo (125 mg sucrose/d) via gelatin capsules in a replicated 4  4 Latin square design. A standard 2-d palatability test also was conducted to examine the palatability of a yeast-containing diet (0.2% of diet). Yeast supplementation did not affect ATTD, fecal characteristics, or fecal fermentative end-products, including short-chain fatty acids, branched-chain fatty acids, indole, and ammonia. Total white blood cell counts were decreased (P < 0.05) by SCFP. The percentage of NK cells and antigen-presenting cells were not altered by SCFP. However, when comparing control vs. all SCFP treatments, SCFP-supplemented dogs had greater (P…
abstract: With growing pet populations and the trend of pet humanization, the demand for functional ingredients that provide health benefits beyond basic nutrition has continued to increase in the pet food industry. Yeast products may serve as functional ingredients due to their potential health benefits as shown in livestock and rodents. Previous studies in dogs demonstrated some positive results of yeast supplementation in terms of modulating a few specific fecal microbiota and immune cell numbers, but little is known regarding the effects of yeast products on immune cell responsiveness, fecal microbiota profiles, and gut integrity. Herein, we aimed to test yeast products and hypothesized that they may provide health benefits and serve as functional ingredients in dog diets by enhancing immune response and promoting intestinal health. The first aim was to evaluate the effects of a Saccharomyces cerevisiae fermentation product (SCFP) on apparent total tract digestibility (ATTD), fecal characteristics, fecal fermentative end-products, fecal microbiota, immune cell populations, immune cell responsiveness, and diet palatability of healthy adult dogs. Twelve healthy adult female beagles (mean age = 3.3 ± 0.8 yr; mean BW = 10.3 ± 0.68 kg) were fed the same diet, but supplemented with 3 levels of yeast fermentation products (125, 250 or 500 mg/d) or a placebo (125 mg sucrose/d) via gelatin capsules in a replicated 4  4 Latin square design. A standard 2-d palatability test also was conducted to examine the palatability of a yeast-containing diet (0.2% of diet). Yeast supplementation did not affect ATTD, fecal characteristics, or fecal fermentative end-products, including short-chain fatty acids, branched-chain fatty acids, indole, and ammonia. Total white blood cell counts were decreased (P < 0.05) by SCFP. The percentage of NK cells and antigen-presenting cells were not altered by SCFP. However, when comparing control vs. all SCFP treatments, SCFP-supplemented dogs had greater (P…
author: Lin, Ching-Yen
language: en
keywords: Yeast product, Dog
date published: 2020-08-27T00:46:48Z
date modified: 2026-07-22T22:24:48Z
provider: University of Illinois - Urbana-Champaign
publisher: Networked Digital Library of Theses and Dissertations
type: WebPage
source organization: University of Illinois at Urbana-Champaign

PropertyValue
property ID: Handle
value: http://hdl.handle.net/2142/108219