{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/105862"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/105862","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"The role of executive functioning in risk for depression: A multi-method longitudinal investigation","abstract":"Broad deficits in executive function (EF) are a common finding in clinical depression. Previously considered to be the result of depression, impaired EF is increasingly recognized as a risk factor that has implications for the onset and course of depression. While the developmental literature indicates that EF deficits prospectively predict future depression, prospective work with adults has been limited. The present studies prospectively assessed whether EF deficits predict future depressive symptoms using multiple measures of EF. Study 1 examined relationships between self-reported EF deficits, a task-based measure of updating working memory (WM), and current and future depressive symptoms among adults who were not selected for psychopathology risk. Study 2 examined relationships among self-reported EF deficits, task-based measures of inhibition, shifting, and updating WM, neural activity during an fMRI task that assessed inhibitory functioning, and current and future depressive symptoms among adults who were selected for psychopathology risk. Study 1 found that broad self-reported EF deficits and the task-based measure of updating WM predicted current and future depressive symptoms, although only self-reported shifting predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Study 2 found that broad self-reported EF predicted current and future depressive symptoms, though only self-reported inhibition and WM predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Only task-based inhibition predicted current depressive symptoms, whereas updating WM and a general measure of EF predicted future depressive symptoms. Furthermore, aberrant neural activity for positive stimuli during the fMRI task predicted future depressive symptoms. Results indicate that, among adults, EF deficits confer risk for future depression.","abstract_html":"Broad deficits in executive function (EF) are a common finding in clinical depression. Previously considered to be the result of depression, impaired EF is increasingly recognized as a risk factor that has implications for the onset and course of depression. While the developmental literature indicates that EF deficits prospectively predict future depression, prospective work with adults has been limited. The present studies prospectively assessed whether EF deficits predict future depressive symptoms using multiple measures of EF. Study 1 examined relationships between self-reported EF deficits, a task-based measure of updating working memory (WM), and current and future depressive symptoms among adults who were not selected for psychopathology risk. Study 2 examined relationships among self-reported EF deficits, task-based measures of inhibition, shifting, and updating WM, neural activity during an fMRI task that assessed inhibitory functioning, and current and future depressive symptoms among adults who were selected for psychopathology risk. Study 1 found that broad self-reported EF deficits and the task-based measure of updating WM predicted current and future depressive symptoms, although only self-reported shifting predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Study 2 found that broad self-reported EF predicted current and future depressive symptoms, though only self-reported inhibition and WM predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Only task-based inhibition predicted current depressive symptoms, whereas updating WM and a general measure of EF predicted future depressive symptoms. Furthermore, aberrant neural activity for positive stimuli during the fMRI task predicted future depressive symptoms. Results indicate that, among adults, EF deficits confer risk for future depression.","abstract_has_math":false,"creators":["Letkiewicz, Allison M."],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Psychology","degree_department":null,"school":null,"contributors":["Heller, Wendy","Berenbaum, Howard","Rudolph, Karen","Hankin, Benjamin","Sutton, Brad"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2019,"date_issued":"2019-11-26T20:58:28Z","date_published":"2019-11-26T20:58:28Z","updated_at":"2026-07-22T22:24:45Z","subjects":["depression, depression risk factors, executive function"],"languages":["en"],"rights":["Copyright 2019 Allison Letkiewicz"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/105862","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Heller, Wendy","Berenbaum, Howard","Rudolph, Karen","Hankin, Benjamin","Sutton, Brad"]},{"key":"dc:creator","label":"Author","values":["Letkiewicz, Allison M."]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2019-11-26T20:58:28Z","2021-11-27T10:15:37Z","2019-06-21","2019-08"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Psychology"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["depression, depression risk factors, executive function"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2019 Allison Letkiewicz"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/105862"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Broad deficits in executive function (EF) are a common finding in clinical depression. Previously considered to be the result of depression, impaired EF is increasingly recognized as a risk factor that has implications for the onset and course of depression. While the developmental literature indicates that EF deficits prospectively predict future depression, prospective work with adults has been limited. The present studies prospectively assessed whether EF deficits predict future depressive symptoms using multiple measures of EF. Study 1 examined relationships between self-reported EF deficits, a task-based measure of updating working memory (WM), and current and future depressive symptoms among adults who were not selected for psychopathology risk. Study 2 examined relationships among self-reported EF deficits, task-based measures of inhibition, shifting, and updating WM, neural activity during an fMRI task that assessed inhibitory functioning, and current and future depressive symptoms among adults who were selected for psychopathology risk. Study 1 found that broad self-reported EF deficits and the task-based measure of updating WM predicted current and future depressive symptoms, although only self-reported shifting predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Study 2 found that broad self-reported EF predicted current and future depressive symptoms, though only self-reported inhibition and WM predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Only task-based inhibition predicted current depressive symptoms, whereas updating WM and a general measure of EF predicted future depressive symptoms. Furthermore, aberrant neural activity for positive stimuli during the fMRI task predicted future depressive symptoms. Results indicate that, among adults, EF deficits confer risk for future depression.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-08-01","The student, Allison Letkiewicz, accepted the attached license on 2019-06-19 at 20:55.","The student, Allison Letkiewicz, submitted this Dissertation for approval on 2019-06-19 at 20:56.","This Dissertation was approved for publication on 2019-06-21 at 08:43.","DSpace SAF Submission Ingestion Package generated from Vireo submission #14023 on 2019-11-26 at 13:59:48","Made available in DSpace on 2019-11-26T20:58:28Z (GMT). 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Previously considered to be the result of depression, impaired EF is increasingly recognized as a risk factor that has implications for the onset and course of depression. While the developmental literature indicates that EF deficits prospectively predict future depression, prospective work with adults has been limited. The present studies prospectively assessed whether EF deficits predict future depressive symptoms using multiple measures of EF. Study 1 examined relationships between self-reported EF deficits, a task-based measure of updating working memory (WM), and current and future depressive symptoms among adults who were not selected for psychopathology risk. Study 2 examined relationships among self-reported EF deficits, task-based measures of inhibition, shifting, and updating WM, neural activity during an fMRI task that assessed inhibitory functioning, and current and future depressive symptoms among adults who were selected for psychopathology risk. Study 1 found that broad self-reported EF deficits and the task-based measure of updating WM predicted current and future depressive symptoms, although only self-reported shifting predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Study 2 found that broad self-reported EF predicted current and future depressive symptoms, though only self-reported inhibition and WM predicted future depressive symptoms after controlling for baseline symptoms of depression and anxiety. Only task-based inhibition predicted current depressive symptoms, whereas updating WM and a general measure of EF predicted future depressive symptoms. Furthermore, aberrant neural activity for positive stimuli during the fMRI task predicted future depressive symptoms. Results indicate that, among adults, EF deficits confer risk for future depression.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-08-01","The student, Allison Letkiewicz, accepted the attached license on 2019-06-19 at 20:55.","The student, Allison Letkiewicz, submitted this Dissertation for approval on 2019-06-19 at 20:56.","This Dissertation was approved for publication on 2019-06-21 at 08:43.","DSpace SAF Submission Ingestion Package generated from Vireo submission #14023 on 2019-11-26 at 13:59:48","Made available in DSpace on 2019-11-26T20:58:28Z (GMT). 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