{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/105236"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/105236","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Spatial dynamics of microbial populations driven by social interactions and horizontal gene transfer","abstract":"The functions of the microbial ecosystems are closely related to the spatial structures formed by microbial communities. Yet, it is not well understood what determines, controls and regulates the spatial dynamics of microbial populations. In this study, we use synthetic microbial consortia as our experimental models, to explore the factors contributing to the microbial populations’ spatial dynamics, owing to their great controllability and reduced system complexity compared to native existing ecosystems. Upon a systematic investigation on the relationship between the microbial spatial structures and factors influencing their spatial dynamics, we found that interaction topologies and horizontal gene transfers drive the spatial structure formations of bacterial communities. Spatial interaction scales, growth rates and antibiotic selection forces are other modulators that affect the spatial structures. Our results confirm social interactions and horizontal gene transfers as two key determinants of the microbial spatial dynamics, providing insights into microbial spatial organization and synthetic ecosystem engineering.","abstract_html":"The functions of the microbial ecosystems are closely related to the spatial structures formed by microbial communities. Yet, it is not well understood what determines, controls and regulates the spatial dynamics of microbial populations. In this study, we use synthetic microbial consortia as our experimental models, to explore the factors contributing to the microbial populations’ spatial dynamics, owing to their great controllability and reduced system complexity compared to native existing ecosystems. Upon a systematic investigation on the relationship between the microbial spatial structures and factors influencing their spatial dynamics, we found that interaction topologies and horizontal gene transfers drive the spatial structure formations of bacterial communities. Spatial interaction scales, growth rates and antibiotic selection forces are other modulators that affect the spatial structures. Our results confirm social interactions and horizontal gene transfers as two key determinants of the microbial spatial dynamics, providing insights into microbial spatial organization and synthetic ecosystem engineering.","abstract_has_math":false,"creators":["Li, Tianyi"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"M.S.","degree_level":"Thesis","degree_discipline":"Bioengineering","degree_department":null,"school":null,"contributors":["Lu, Ting"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2019,"date_issued":"2019-08-23T20:48:21Z","date_published":"2019-08-23T20:48:21Z","updated_at":"2026-07-22T22:24:44Z","subjects":["Spatial Dynamics, Synthetic Ecosystems."],"languages":["en"],"rights":["Copyright 2019 Tianyi Li"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/105236","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Lu, Ting"]},{"key":"dc:creator","label":"Author","values":["Li, Tianyi"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2019-08-23T20:48:21Z","2021-08-24T09:15:10Z","2019-04-23","2019-05"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Bioengineering"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Spatial Dynamics, Synthetic Ecosystems."]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2019 Tianyi Li"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/105236"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["The functions of the microbial ecosystems are closely related to the spatial structures formed by microbial communities. Yet, it is not well understood what determines, controls and regulates the spatial dynamics of microbial populations. In this study, we use synthetic microbial consortia as our experimental models, to explore the factors contributing to the microbial populations’ spatial dynamics, owing to their great controllability and reduced system complexity compared to native existing ecosystems. Upon a systematic investigation on the relationship between the microbial spatial structures and factors influencing their spatial dynamics, we found that interaction topologies and horizontal gene transfers drive the spatial structure formations of bacterial communities. Spatial interaction scales, growth rates and antibiotic selection forces are other modulators that affect the spatial structures. Our results confirm social interactions and horizontal gene transfers as two key determinants of the microbial spatial dynamics, providing insights into microbial spatial organization and synthetic ecosystem engineering.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-05-01","The student, Tianyi Li, accepted the attached license on 2019-04-19 at 16:32.","The student, Tianyi Li, submitted this Thesis for approval on 2019-04-19 at 16:58.","This Thesis was approved for publication on 2019-04-23 at 15:20.","DSpace SAF Submission Ingestion Package generated from Vireo submission #13796 on 2019-08-22 at 16:23:25","Made available in DSpace on 2019-08-23T20:48:21Z (GMT). No. of bitstreams: 2 LI-THESIS-2019.pdf: 5338866 bytes, checksum: b1ad5c95f89e85263d1dcdfa06c95f6b (MD5) LICENSE.txt: 4206 bytes, checksum: 24babf9d56c2687a0522d2455dda8baa (MD5) Previous issue date: 2019-04-23","Embargo set by: Seth Robbins for item 112358 Lift date: 2021-08-23T20:48:32Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system","Limited Restriction Lifted for Item 112358 on 2021-08-24T09:15:10Z."]},{"key":"dc:format","label":"Dc Format","values":["application/pdf"]},{"key":"dc:title","label":"Title","values":["Spatial dynamics of microbial populations driven by social interactions and horizontal gene transfer"]}]}],"canonical_facts":{"dc:contributor":["Lu, Ting"],"dc:creator":["Li, Tianyi"],"dc:date":["2019-08-23T20:48:21Z","2021-08-24T09:15:10Z","2019-04-23","2019-05"],"dc:description":["The functions of the microbial ecosystems are closely related to the spatial structures formed by microbial communities. Yet, it is not well understood what determines, controls and regulates the spatial dynamics of microbial populations. In this study, we use synthetic microbial consortia as our experimental models, to explore the factors contributing to the microbial populations’ spatial dynamics, owing to their great controllability and reduced system complexity compared to native existing ecosystems. Upon a systematic investigation on the relationship between the microbial spatial structures and factors influencing their spatial dynamics, we found that interaction topologies and horizontal gene transfers drive the spatial structure formations of bacterial communities. Spatial interaction scales, growth rates and antibiotic selection forces are other modulators that affect the spatial structures. Our results confirm social interactions and horizontal gene transfers as two key determinants of the microbial spatial dynamics, providing insights into microbial spatial organization and synthetic ecosystem engineering.","Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2021-05-01","The student, Tianyi Li, accepted the attached license on 2019-04-19 at 16:32.","The student, Tianyi Li, submitted this Thesis for approval on 2019-04-19 at 16:58.","This Thesis was approved for publication on 2019-04-23 at 15:20.","DSpace SAF Submission Ingestion Package generated from Vireo submission #13796 on 2019-08-22 at 16:23:25","Made available in DSpace on 2019-08-23T20:48:21Z (GMT). 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