{"id":{"repo_id":"uiuc","oai_identifier":"oai:www.ideals.illinois.edu:2142/100891"},"canonical_url":"https://search.dev.ndltd.org/etd/uiuc/oai:www.ideals.illinois.edu:2142/100891","repository":{"repo_id":"uiuc","name":"University of Illinois - Urbana-Champaign","base_url":"https://www.ideals.illinois.edu/oai-pmh"},"display":{"title":"Shedding light on E. coli phototaxis","abstract":"My thesis work has been focused on phototaxis response in E. coli. I will review the current state of knowledge on chemotaxis and phototaxis and discuss the motivation behind this project in Chapter 1. In Chapters 2 and 3, I will describe a high-throughput framework for studying phototaxis in bacteria, which consists of the experimental setup and automated routine for data analysis, that I have developed over the course of this project. In Chapter 4, I will present experimental results that allowed us to pinpoint the role of individual components of the chemotactic network in phototaxis response and to characterize power dependence of the response. In Chapter 5, I will discuss the role of receptor-receptor interaction in determining the integrated phototactic response. In Chapter 6, I will quantify the effect of light on E. coli swimming velocity and its potential implication. In Chapter 7, I will discuss how various external parameters affect E. coli phototaxis response. Finally, in Chapter 8, I will present some preliminary results and discuss potential future directions of this project.","abstract_html":"My thesis work has been focused on phototaxis response in E. coli. I will review the current state of knowledge on chemotaxis and phototaxis and discuss the motivation behind this project in Chapter 1. In Chapters 2 and 3, I will describe a high-throughput framework for studying phototaxis in bacteria, which consists of the experimental setup and automated routine for data analysis, that I have developed over the course of this project. In Chapter 4, I will present experimental results that allowed us to pinpoint the role of individual components of the chemotactic network in phototaxis response and to characterize power dependence of the response. In Chapter 5, I will discuss the role of receptor-receptor interaction in determining the integrated phototactic response. In Chapter 6, I will quantify the effect of light on E. coli swimming velocity and its potential implication. In Chapter 7, I will discuss how various external parameters affect E. coli phototaxis response. Finally, in Chapter 8, I will present some preliminary results and discuss potential future directions of this project.","abstract_has_math":false,"creators":["Perlova, Tatyana Yurievna"],"institution":"University of Illinois at Urbana-Champaign","degree_name":"Ph.D.","degree_level":"Dissertation","degree_discipline":"Physics","degree_department":null,"school":null,"contributors":["Gruebele, Martin","Chemla, Yann R.","Rao, Christopher","Shukla, Diwakar"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2018,"date_issued":"2018-09-04T20:26:30Z","date_published":"2018-09-04T20:26:30Z","updated_at":"2026-07-22T22:24:38Z","subjects":["Escherichia coli, chemotaxis, phototaxis"],"languages":["en"],"rights":["Copyright 2017 Tatyana Perlova"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"http://hdl.handle.net/2142/100891","outbound_label":"Handle","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Gruebele, Martin","Chemla, Yann R.","Rao, Christopher","Shukla, Diwakar"]},{"key":"dc:creator","label":"Author","values":["Perlova, Tatyana Yurievna"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2018-09-04T20:26:30Z","2018-01-22","2018-05"]},{"key":"dc:type","label":"Dc Type","values":["text"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Physics"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Dissertation"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Ph.D."]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["University of Illinois at Urbana-Champaign"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Escherichia coli, chemotaxis, phototaxis"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language","label":"Dc Language","values":["en"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright 2017 Tatyana Perlova"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["http://hdl.handle.net/2142/100891"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["My thesis work has been focused on phototaxis response in E. coli. I will review the current state of knowledge on chemotaxis and phototaxis and discuss the motivation behind this project in Chapter 1. In Chapters 2 and 3, I will describe a high-throughput framework for studying phototaxis in bacteria, which consists of the experimental setup and automated routine for data analysis, that I have developed over the course of this project. In Chapter 4, I will present experimental results that allowed us to pinpoint the role of individual components of the chemotactic network in phototaxis response and to characterize power dependence of the response. In Chapter 5, I will discuss the role of receptor-receptor interaction in determining the integrated phototactic response. In Chapter 6, I will quantify the effect of light on E. coli swimming velocity and its potential implication. In Chapter 7, I will discuss how various external parameters affect E. coli phototaxis response. Finally, in Chapter 8, I will present some preliminary results and discuss potential future directions of this project.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2018-08-31 without embargo terms","The student, Tatyana Perlova, accepted the attached license on 2018-01-15 at 13:39.","The student, Tatyana Perlova, submitted this Dissertation for approval on 2018-01-15 at 13:49.","This Dissertation was approved for publication on 2018-01-22 at 15:01.","DSpace SAF Submission Ingestion Package generated from Vireo submission #12009 on 2018-08-31 at 17:08:03","Made available in DSpace on 2018-09-04T20:26:30Z (GMT). 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In Chapters 2 and 3, I will describe a high-throughput framework for studying phototaxis in bacteria, which consists of the experimental setup and automated routine for data analysis, that I have developed over the course of this project. In Chapter 4, I will present experimental results that allowed us to pinpoint the role of individual components of the chemotactic network in phototaxis response and to characterize power dependence of the response. In Chapter 5, I will discuss the role of receptor-receptor interaction in determining the integrated phototactic response. In Chapter 6, I will quantify the effect of light on E. coli swimming velocity and its potential implication. In Chapter 7, I will discuss how various external parameters affect E. coli phototaxis response. Finally, in Chapter 8, I will present some preliminary results and discuss potential future directions of this project.","Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2018-08-31 without embargo terms","The student, Tatyana Perlova, accepted the attached license on 2018-01-15 at 13:39.","The student, Tatyana Perlova, submitted this Dissertation for approval on 2018-01-15 at 13:49.","This Dissertation was approved for publication on 2018-01-22 at 15:01.","DSpace SAF Submission Ingestion Package generated from Vireo submission #12009 on 2018-08-31 at 17:08:03","Made available in DSpace on 2018-09-04T20:26:30Z (GMT). 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