Analytical Modeling of Optical Coherence Tomography

Optical Coherence Tomography (OCT) has become an indispensable imaging modality in ophthalmology and dermatology, prized for its micrometer-level resolution, non-invasiveness, and significant penetration depth. Despite its precision in revealing skin morphology, standard OCT lacks the ability to help dermatologists reliably differentiate between early-stage cancerous melanoma and benign nevi. This research addresses this critical diagnostic gap by introducing a novel analytical model to extract objective optical features from OCT images. This model is founded on the extended Huygens-Fresnel principle and complex ray matrices, uniquely accounting for wavelength-dependent optical properties and illumination. This framework not only improves diagnostics but also opens avenues for enhancing OCT system design via bandwidth tuning. Ultimately, the model's hardware independence and strong potential for clinical translation establish it as a powerful and broadly applicable diagnostic tool, well beyond its initial application in dermatology.

Author dc:creator

• Sina Movahedi Aliabadi (23292154)

• Engineering, Electronics and Electrical
• Engineering, Biomedical
• Health Sciences, Medicine and Surgery

Statement dc:rights

• In Copyright
• Open Access after 2028-01-01

DOI dc:identifier

https://doi.org/10.25417/uic.31451914.v1

OAI identifier oai:identifier

oai:figshare.com:article/31451914