{"id":{"repo_id":"uic","oai_identifier":"oai:figshare.com:article/30425002"},"canonical_url":"https://search.dev.ndltd.org/etd/uic/oai:figshare.com:article/30425002","repository":{"repo_id":"uic","name":"University of Illinois - Chicago","base_url":"https://api.figshare.com/v2/oai"},"display":{"title":"Molar Incisor Hypomineralization and Developmental Dental Anomalies: A Case-Control Study","abstract":"Title: Molar Incisor Hypomineralization and Dental Anomalies: A Case-Control Study Authors : Park J1, Kratunova E1, Alrayyes S1, Alsaleh M1,Galang-Boquiren M2, Ahmed AT 1 Author affiliations :1 Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA Objectives: To evaluate the association between Molar Incisor Hypomineralization (MIH), early-life adverse environmental and medical events, and co-existing developmental dental anomalies (DDA). Methods: This case-control study included children aged 6–13 years, with the presence of MIH serving as the inclusion criterion for the case group. Each child with MIH was matched with a child without MIH of similar age and demographic characteristics to form the control group. Trained and calibrated examiners assessed MIH using standardized diagnostic criteria. Biological mothers completed a structured questionnaire addressing pregnancy and early-life adverse events. DDA were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher’s exact tests, and logistic regression. Results: A total of 56 children were enrolled, including 28 in the MIH group and 28 in the control group. The mean age was 9.32 ± 1.89 years in the MIH group and 8.24 ± 1.46 years in the control group. Among the MIH group, 89.3% were born in the United States compared to 96.3% in the control group, and 70.4% were Hispanic or Latino compared to 78.6% in the control group. Developmental dental anomalies were significantly associated with MIH (χ² = 6.76, P = .0093). No significant differences were found in pregnancy, environmental and early-life adverse events between the MIH and control groups (P > .05). Conclusions: This preliminary study demonstrates a significant association between MIH and the presence of DDA. Further research with larger sample sizes is needed to confirm these findings.","abstract_html":"Title: Molar Incisor Hypomineralization and Dental Anomalies: A Case-Control Study Authors : Park J1, Kratunova E1, Alrayyes S1, Alsaleh M1,Galang-Boquiren M2, Ahmed AT 1 Author affiliations :1 Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA Objectives: To evaluate the association between Molar Incisor Hypomineralization (MIH), early-life adverse environmental and medical events, and co-existing developmental dental anomalies (DDA). Methods: This case-control study included children aged 6–13 years, with the presence of MIH serving as the inclusion criterion for the case group. Each child with MIH was matched with a child without MIH of similar age and demographic characteristics to form the control group. Trained and calibrated examiners assessed MIH using standardized diagnostic criteria. Biological mothers completed a structured questionnaire addressing pregnancy and early-life adverse events. DDA were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher’s exact tests, and logistic regression. Results: A total of 56 children were enrolled, including 28 in the MIH group and 28 in the control group. The mean age was 9.32 ± 1.89 years in the MIH group and 8.24 ± 1.46 years in the control group. Among the MIH group, 89.3% were born in the United States compared to 96.3% in the control group, and 70.4% were Hispanic or Latino compared to 78.6% in the control group. Developmental dental anomalies were significantly associated with MIH (χ² = 6.76, P = .0093). No significant differences were found in pregnancy, environmental and early-life adverse events between the MIH and control groups (P > .05). Conclusions: This preliminary study demonstrates a significant association between MIH and the presence of DDA. Further research with larger sample sizes is needed to confirm these findings.","abstract_has_math":false,"creators":["Juno Park (22481752)"],"institution":null,"degree_name":null,"degree_level":null,"degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2025,"date_issued":"2025-08-01T00:00:00Z","date_published":"2025-08-01T00:00:00Z","updated_at":"2026-07-27T21:34:45Z","subjects":["Health Sciences","Dentistry"],"languages":[],"rights":["In Copyright"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://doi.org/10.25417/uic.30425002.v1","outbound_label":"DOI","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Juno Park (22481752)"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2025-08-01T00:00:00Z"]},{"key":"dc:relation","label":"Dc Relation","values":["https://figshare.com/articles/thesis/Molar_Incisor_Hypomineralization_and_Developmental_Dental_Anomalies_A_Case-Control_Study/30425002"]},{"key":"dc:type","label":"Dc Type","values":["Text","Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Health Sciences","Dentistry"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["In Copyright"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["10.25417/uic.30425002.v1"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Title: Molar Incisor Hypomineralization and Dental Anomalies: A Case-Control Study Authors : Park J1, Kratunova E1, Alrayyes S1, Alsaleh M1,Galang-Boquiren M2, Ahmed AT 1 Author affiliations :1 Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA Objectives: To evaluate the association between Molar Incisor Hypomineralization (MIH), early-life adverse environmental and medical events, and co-existing developmental dental anomalies (DDA). Methods: This case-control study included children aged 6–13 years, with the presence of MIH serving as the inclusion criterion for the case group. Each child with MIH was matched with a child without MIH of similar age and demographic characteristics to form the control group. Trained and calibrated examiners assessed MIH using standardized diagnostic criteria. Biological mothers completed a structured questionnaire addressing pregnancy and early-life adverse events. DDA were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher’s exact tests, and logistic regression. Results: A total of 56 children were enrolled, including 28 in the MIH group and 28 in the control group. The mean age was 9.32 ± 1.89 years in the MIH group and 8.24 ± 1.46 years in the control group. Among the MIH group, 89.3% were born in the United States compared to 96.3% in the control group, and 70.4% were Hispanic or Latino compared to 78.6% in the control group. Developmental dental anomalies were significantly associated with MIH (χ² = 6.76, P = .0093). No significant differences were found in pregnancy, environmental and early-life adverse events between the MIH and control groups (P > .05). Conclusions: This preliminary study demonstrates a significant association between MIH and the presence of DDA. Further research with larger sample sizes is needed to confirm these findings."]},{"key":"dc:title","label":"Title","values":["Molar Incisor Hypomineralization and Developmental Dental Anomalies: A Case-Control Study"]}]}],"canonical_facts":{"dc:creator":["Juno Park (22481752)"],"dc:date":["2025-08-01T00:00:00Z"],"dc:description":["Title: Molar Incisor Hypomineralization and Dental Anomalies: A Case-Control Study Authors : Park J1, Kratunova E1, Alrayyes S1, Alsaleh M1,Galang-Boquiren M2, Ahmed AT 1 Author affiliations :1 Department of Pediatric Dentistry, College of Dentistry, University of Illinois, Chicago, IL, USA Objectives: To evaluate the association between Molar Incisor Hypomineralization (MIH), early-life adverse environmental and medical events, and co-existing developmental dental anomalies (DDA). Methods: This case-control study included children aged 6–13 years, with the presence of MIH serving as the inclusion criterion for the case group. Each child with MIH was matched with a child without MIH of similar age and demographic characteristics to form the control group. Trained and calibrated examiners assessed MIH using standardized diagnostic criteria. Biological mothers completed a structured questionnaire addressing pregnancy and early-life adverse events. DDA were identified through clinical and radiographic assessment. Statistical analyses included descriptive statistics, Chi-square and Fisher’s exact tests, and logistic regression. Results: A total of 56 children were enrolled, including 28 in the MIH group and 28 in the control group. The mean age was 9.32 ± 1.89 years in the MIH group and 8.24 ± 1.46 years in the control group. Among the MIH group, 89.3% were born in the United States compared to 96.3% in the control group, and 70.4% were Hispanic or Latino compared to 78.6% in the control group. Developmental dental anomalies were significantly associated with MIH (χ² = 6.76, P = .0093). No significant differences were found in pregnancy, environmental and early-life adverse events between the MIH and control groups (P > .05). Conclusions: This preliminary study demonstrates a significant association between MIH and the presence of DDA. Further research with larger sample sizes is needed to confirm these findings."],"dc:identifier":["10.25417/uic.30425002.v1"],"dc:relation":["https://figshare.com/articles/thesis/Molar_Incisor_Hypomineralization_and_Developmental_Dental_Anomalies_A_Case-Control_Study/30425002"],"dc:rights":["In Copyright"],"dc:subject":["Health Sciences","Dentistry"],"dc:title":["Molar Incisor Hypomineralization and Developmental Dental Anomalies: A Case-Control Study"],"dc:type":["Text","Thesis"]},"updated_at":"2026-07-27T21:34:45Z"}