The highly porous Mn2O3-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination) and then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. A notable enhancement of direct electron transfer between GOD and the electrode is observed at the Mn2O3-Ag-GOD modified electrode with a fast electron transfer rate constant. The biosensor also shows fast response to glucose, high sensitivity (40.60 μA×mM-1×cm-2), low detection limit (1.73 µM at S/N=3), low Km,app value and excellent selectivity. These results indicate that the novel Mn2O3-Ag nanfibers-GOD composite has great potential application in oxygen-reduction-based glucose biosensing.
","abstract_html":"<p>The highly porous Mn<sub>2</sub>O<sub>3</sub>-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination) and then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. A notable enhancement of direct electron transfer between GOD and the electrode is observed at the Mn<sub>2</sub>O<sub>3</sub>-Ag-GOD modified electrode with a fast electron transfer rate constant. The biosensor also shows fast response to glucose, high sensitivity (40.60 μA×mM<sup>-1</sup>×cm<sup>-2</sup>), low detection limit (1.73 µM at S/N=3), low <em>K</em><sub>m,app </sub>value and excellent selectivity. These results indicate that the novel Mn<sub>2</sub>O<sub>3</sub>-Ag nanfibers-GOD composite has great potential application in oxygen-reduction-based glucose biosensing.</p>","abstract_has_math":false,"creators":["Huang, Shan"],"institution":null,"degree_name":"Master of Science","degree_level":null,"degree_discipline":"Biomedical Engineering","degree_department":null,"school":null,"contributors":["Baikun Li; William Mustain","Yu Lei"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2011,"date_issued":"2011-08-22T07:00:00Z","date_published":"2011-08-22T07:00:00Z","updated_at":"2026-07-24T06:31:45Z","subjects":["Diabetes","Glucose","GOD","Maganese Oxide"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.lib.uconn.edu/gs_theses/147","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Baikun Li; William Mustain","Yu Lei"]},{"key":"dc:creator","label":"Author","values":["Huang, Shan"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2011-08-22T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Engineering"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Diabetes","Glucose","GOD","Maganese Oxide"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.lib.uconn.edu/gs_theses/147"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["The highly porous Mn2O3-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination) and then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. A notable enhancement of direct electron transfer between GOD and the electrode is observed at the Mn2O3-Ag-GOD modified electrode with a fast electron transfer rate constant. The biosensor also shows fast response to glucose, high sensitivity (40.60 μA×mM-1×cm-2), low detection limit (1.73 µM at S/N=3), low Km,app value and excellent selectivity. These results indicate that the novel Mn2O3-Ag nanfibers-GOD composite has great potential application in oxygen-reduction-based glucose biosensing.
"]},{"key":"dc:title","label":"Title","values":["Glucose Biosensor Using Electrospun Mn2O3-Ag Nanofibers"]}]}],"canonical_facts":{"dc:contributor":["Baikun Li; William Mustain","Yu Lei"],"dc:creator":["Huang, Shan"],"dc:date.available":["2011-08-22T07:00:00Z"],"dc:description.abstract":["The highly porous Mn2O3-Ag nanofibers were fabricated by a facile two-step procedure (electrospinning and calcination) and then employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric glucose biosensor. A notable enhancement of direct electron transfer between GOD and the electrode is observed at the Mn2O3-Ag-GOD modified electrode with a fast electron transfer rate constant. The biosensor also shows fast response to glucose, high sensitivity (40.60 μA×mM-1×cm-2), low detection limit (1.73 µM at S/N=3), low Km,app value and excellent selectivity. These results indicate that the novel Mn2O3-Ag nanfibers-GOD composite has great potential application in oxygen-reduction-based glucose biosensing.
"],"dc:identifier":["https://digitalcommons.lib.uconn.edu/gs_theses/147"],"dc:subject":["Diabetes","Glucose","GOD","Maganese Oxide"],"dc:title":["Glucose Biosensor Using Electrospun Mn2O3-Ag Nanofibers"],"thesis:degree_discipline":["Biomedical Engineering"],"thesis:degree_name":["Master of Science"]},"updated_at":"2026-07-24T06:31:45Z"}