{"id":{"repo_id":"uab","oai_identifier":"oai:digitalcommons.library.uab.edu:etd-collection-8100"},"canonical_url":"https://search.dev.ndltd.org/etd/uab/oai:digitalcommons.library.uab.edu:etd-collection-8100","repository":{"repo_id":"uab","name":"University of Alabama Birmingham","base_url":"https://digitalcommons.library.uab.edu/do/oai/"},"display":{"title":"Some Effects of 6-Azauridine on Two Mutant Genes in the Mouse.","abstract":"Certain instances of abnormal development may be due to genotype alone or to environment alone. In all likelihood, however, most abnormal development results from an interaction of genotype and environment (Fraser, ’59). The influence of genotype on response to environmental stimuli has been investigated in Drosophila (Goldschmidt and Piternick, ’57), fowl (Landauer, ’48, ’60, ’65), and mammals (Dagg, ’66). Different strains of the same species often show varied developmental responses to the same stimulus, presumably due to polygenic differences between strains (Dagg, ’63; Dagg, Schlager and Doer, ’65; Landauer, *60). Also, single gene differences within a strain may alter the response of a developing organism to environment (Goldschmidt and Piternick, ’57; Landauer, ’60, ’65; Smithberg, ’67).","abstract_html":"Certain instances of abnormal development may be due to genotype alone or to environment alone. In all likelihood, however, most abnormal development results from an interaction of genotype and environment (Fraser, ’59). The influence of genotype on response to environmental stimuli has been investigated in Drosophila (Goldschmidt and Piternick, ’57), fowl (Landauer, ’48, ’60, ’65), and mammals (Dagg, ’66). Different strains of the same species often show varied developmental responses to the same stimulus, presumably due to polygenic differences between strains (Dagg, ’63; Dagg, Schlager and Doer, ’65; Landauer, *60). Also, single gene differences within a strain may alter the response of a developing organism to environment (Goldschmidt and Piternick, ’57; Landauer, ’60, ’65; Smithberg, ’67).","abstract_has_math":false,"creators":["Musgrove, John Larkin"],"institution":null,"degree_name":null,"degree_level":"Thesis","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1973,"date_issued":"1973-01-01T08:00:00Z","date_published":"1973-01-01T08:00:00Z","updated_at":"2026-07-24T05:05:33Z","subjects":["Abnormal development","Genotype","Environmental stimuli","Gene differences","Drosophila"],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://digitalcommons.library.uab.edu/etd-collection/7108","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:creator","label":"Author","values":["Musgrove, John Larkin"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Abnormal development","Genotype","Environmental stimuli","Gene differences","Drosophila"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://digitalcommons.library.uab.edu/etd-collection/7108"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Certain instances of abnormal development may be due to genotype alone or to environment alone. In all likelihood, however, most abnormal development results from an interaction of genotype and environment (Fraser, ’59). The influence of genotype on response to environmental stimuli has been investigated in Drosophila (Goldschmidt and Piternick, ’57), fowl (Landauer, ’48, ’60, ’65), and mammals (Dagg, ’66). Different strains of the same species often show varied developmental responses to the same stimulus, presumably due to polygenic differences between strains (Dagg, ’63; Dagg, Schlager and Doer, ’65; Landauer, *60). Also, single gene differences within a strain may alter the response of a developing organism to environment (Goldschmidt and Piternick, ’57; Landauer, ’60, ’65; Smithberg, ’67)."]},{"key":"dc:title","label":"Title","values":["Some Effects of 6-Azauridine on Two Mutant Genes in the Mouse."]}]}],"canonical_facts":{"dc:creator":["Musgrove, John Larkin"],"dc:description.abstract":["Certain instances of abnormal development may be due to genotype alone or to environment alone. In all likelihood, however, most abnormal development results from an interaction of genotype and environment (Fraser, ’59). The influence of genotype on response to environmental stimuli has been investigated in Drosophila (Goldschmidt and Piternick, ’57), fowl (Landauer, ’48, ’60, ’65), and mammals (Dagg, ’66). Different strains of the same species often show varied developmental responses to the same stimulus, presumably due to polygenic differences between strains (Dagg, ’63; Dagg, Schlager and Doer, ’65; Landauer, *60). Also, single gene differences within a strain may alter the response of a developing organism to environment (Goldschmidt and Piternick, ’57; Landauer, ’60, ’65; Smithberg, ’67)."],"dc:identifier":["https://digitalcommons.library.uab.edu/etd-collection/7108"],"dc:subject":["Abnormal development","Genotype","Environmental stimuli","Gene differences","Drosophila"],"dc:title":["Some Effects of 6-Azauridine on Two Mutant Genes in the Mouse."],"thesis:degree_level":["Thesis"]},"updated_at":"2026-07-24T05:05:33Z"}