For centuries, men have known that the skin of toads and other amphibians possess pharmacologically active compounds (Abel and Nacht,1911;Chen and Jensen,1929;Chen and Kovarikova,1967).All amphibians produce toxins in glands scattered over the skin .Many anuran amphibians have parotoid glands located on the lateral ,anterior ldorsal surface which are apparently specialized for the secretion of large quantities of toxin. W'eiss(1899) and Muhse(1909) describe the histology of these glands.
","abstract_html":"<p>For centuries, men have known that the skin of toads and other amphibians possess pharmacologically active compounds (Abel and Nacht,1911;Chen and Jensen,1929;Chen and Kovarikova,1967).All amphibians produce toxins in glands scattered over the skin .Many anuran amphibians have parotoid glands located on the lateral ,anterior ldorsal surface which are apparently specialized for the secretion of large quantities of toxin. W'eiss(1899) and Muhse(1909) describe the histology of these glands.</p>","abstract_has_math":false,"creators":["Knickelbein, Roy Gordon"],"institution":null,"degree_name":"Master of Science (M.S.)","degree_level":"Thesis","degree_discipline":"Biological Sciences","degree_department":null,"school":null,"contributors":["A. Mathias"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1972,"date_issued":"1972-01-01T08:00:00Z","date_published":"1972-01-01T08:00:00Z","updated_at":"2026-07-24T05:37:42Z","subjects":["Toads","Effect of drugs on","Veterinary pharmacology","Biology","Life Sciences","Pharmacology"],"languages":[],"rights":[],"rights_urls":["http://rightsstatements.org/vocab/NKC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"https://scholarlycommons.pacific.edu/uop_etds/1766","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["A. Mathias"]},{"key":"dc:creator","label":"Author","values":["Knickelbein, Roy Gordon"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["2018-06-29T07:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Biological Sciences"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Toads","Effect of drugs on","Veterinary pharmacology","Biology","Life Sciences","Pharmacology"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["http://rightsstatements.org/vocab/NKC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarlycommons.pacific.edu/uop_etds/1766"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["For centuries, men have known that the skin of toads and other amphibians possess pharmacologically active compounds (Abel and Nacht,1911;Chen and Jensen,1929;Chen and Kovarikova,1967).All amphibians produce toxins in glands scattered over the skin .Many anuran amphibians have parotoid glands located on the lateral ,anterior ldorsal surface which are apparently specialized for the secretion of large quantities of toxin. W'eiss(1899) and Muhse(1909) describe the histology of these glands.
"]},{"key":"dc:title","label":"Title","values":["Pharmacological effects of a bufadienolide isolated from the toad Bufo boreas halophilus"]}]}],"canonical_facts":{"dc:contributor":["A. Mathias"],"dc:creator":["Knickelbein, Roy Gordon"],"dc:date.available":["2018-06-29T07:00:00Z"],"dc:description.abstract":["For centuries, men have known that the skin of toads and other amphibians possess pharmacologically active compounds (Abel and Nacht,1911;Chen and Jensen,1929;Chen and Kovarikova,1967).All amphibians produce toxins in glands scattered over the skin .Many anuran amphibians have parotoid glands located on the lateral ,anterior ldorsal surface which are apparently specialized for the secretion of large quantities of toxin. W'eiss(1899) and Muhse(1909) describe the histology of these glands.
"],"dc:identifier":["https://scholarlycommons.pacific.edu/uop_etds/1766"],"dc:rights":["http://rightsstatements.org/vocab/NKC/1.0/"],"dc:subject":["Toads","Effect of drugs on","Veterinary pharmacology","Biology","Life Sciences","Pharmacology"],"dc:title":["Pharmacological effects of a bufadienolide isolated from the toad Bufo boreas halophilus"],"thesis:degree_discipline":["Biological Sciences"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (M.S.)"]},"updated_at":"2026-07-24T05:37:42Z"}