A study of the platinum (II), palladium (II), and rhodium (III) chelates of aspartic and glutamic acid
It is fairly well known that alpha-amino dicarboxylic acids combine quite readily with basic metal ions such as the alkaline earths. The nature of the problem includes the synthesis and characterization of six platinum metal chelates of two alpha-animo dicarboxylic acids, namely aspartic and glutamic acids. The metal ion upon which the investigation is focused are platinum (II), palladium (II), and rhodium (III). Several of these are reported as having been repaired. The series is incomplete, however, and little study has been done correlating the abilities and trends of the complexes as a function of the metal ion and carbon chain length of the ligand acid molecule. Hence, the ultimate aim of the investigation is to study the tendency of chelation as the carbon chain length of the alpha-amino dicarboxylic acid increases and also to study the stability of the chelates as the central metal ion is varied. Because there are numerous problems involved here, the investigation extends somewhat beyond the scope of a Master’s research. Therefore the investigation is limited only to aspartic and glutamic acid. The methods of synthesis for the palladium, platinum, and rhodium chelates of aspartic and glutamic acids were studied and outlined. After synthesis, the means which were employed for characterization included elemental analysis, molecular weight determination, and infrared and ultraviolet spectra.
Amino acid chelates, Chemistry, Physical Sciences and Mathematics
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