In most hospitals today, plastic devices are replacing the traditional metal, glass and rubber. The increased use of polymeric materials as implanted prosthetic devices, catheters, disposable equipment and for the administration of blood, intravenous fluids and drugs has been widely accepted by the medical profession.
This present study was designed to evaluate different types of plastics for potential use as large volume parenteral containers. Using several different therapeutic agents, a variety of plastic containers were examined for the possibility of the occurrence of drug-plastic interactions. The inclusion in the study of a commercially available plasticized product used for the administration of parenteral solutions was to compare the results of commercial products to non-commercial products.","abstract_html":"<p>In most hospitals today, plastic devices are replacing the traditional metal, glass and rubber. The increased use of polymeric materials as implanted prosthetic devices, catheters, disposable equipment and for the administration of blood, intravenous fluids and drugs has been widely accepted by the medical profession.</p>This present study was designed to evaluate different types of plastics for potential use as large volume parenteral containers. Using several different therapeutic agents, a variety of plastic containers were examined for the possibility of the occurrence of drug-plastic interactions. The inclusion in the study of a commercially available plasticized product used for the administration of parenteral solutions was to compare the results of commercial products to non-commercial products.</p>","abstract_has_math":false,"creators":["Smith, Charles Arthur"],"institution":null,"degree_name":"Master of Science (M.S.)","degree_level":"Thesis","degree_discipline":"Graduate School","degree_department":null,"school":null,"contributors":["James C. King"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1979,"date_issued":"1979-01-01T08:00:00Z","date_published":"1979-01-01T08:00:00Z","updated_at":"2026-07-24T05:36:21Z","subjects":["Drugs Packaging","Plastics in medicine","Plastic containers","Drug interactions","Medicine and Health Sciences"],"languages":[],"rights":[],"rights_urls":["http://rightsstatements.org/vocab/NKC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"https://scholarlycommons.pacific.edu/uop_etds/447","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["James C. King"]},{"key":"dc:creator","label":"Author","values":["Smith, Charles Arthur"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["1979-01-01T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Graduate School"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Drugs Packaging","Plastics in medicine","Plastic containers","Drug interactions","Medicine and Health Sciences"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["http://rightsstatements.org/vocab/NKC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarlycommons.pacific.edu/uop_etds/447"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["In most hospitals today, plastic devices are replacing the traditional metal, glass and rubber. The increased use of polymeric materials as implanted prosthetic devices, catheters, disposable equipment and for the administration of blood, intravenous fluids and drugs has been widely accepted by the medical profession.
This present study was designed to evaluate different types of plastics for potential use as large volume parenteral containers. Using several different therapeutic agents, a variety of plastic containers were examined for the possibility of the occurrence of drug-plastic interactions. The inclusion in the study of a commercially available plasticized product used for the administration of parenteral solutions was to compare the results of commercial products to non-commercial products."]},{"key":"dc:source","label":"Dc Source","values":["62"]},{"key":"dc:title","label":"Title","values":["A study of drug-plastic interactions in a variety of plastic containers"]}]}],"canonical_facts":{"dc:contributor":["James C. King"],"dc:creator":["Smith, Charles Arthur"],"dc:date.available":["1979-01-01T08:00:00Z"],"dc:description.abstract":["In most hospitals today, plastic devices are replacing the traditional metal, glass and rubber. The increased use of polymeric materials as implanted prosthetic devices, catheters, disposable equipment and for the administration of blood, intravenous fluids and drugs has been widely accepted by the medical profession.
This present study was designed to evaluate different types of plastics for potential use as large volume parenteral containers. Using several different therapeutic agents, a variety of plastic containers were examined for the possibility of the occurrence of drug-plastic interactions. The inclusion in the study of a commercially available plasticized product used for the administration of parenteral solutions was to compare the results of commercial products to non-commercial products."],"dc:identifier":["https://scholarlycommons.pacific.edu/uop_etds/447"],"dc:rights":["http://rightsstatements.org/vocab/NKC/1.0/"],"dc:source":["62"],"dc:subject":["Drugs Packaging","Plastics in medicine","Plastic containers","Drug interactions","Medicine and Health Sciences"],"dc:title":["A study of drug-plastic interactions in a variety of plastic containers"],"thesis:degree_discipline":["Graduate School"],"thesis:degree_level":["Thesis"],"thesis:degree_name":["Master of Science (M.S.)"]},"updated_at":"2026-07-24T05:36:21Z"}