Through the years, various studies (1-5) have been done regarding the prevalent practice of adding one or more drugs to parenteral fluids. The greater variety of drugs being used intravenously, plus the formulation of newer and more complex parenteral fluids, has led to an increased awareness of potential incompatibilities existing between drug and solution. Recognition of the hazards of such extemporaneous combinations has necessitated the study of drug stability in solution.
The objective of this report is to determine compatibility characteristics of admixtures prepared from a series of balance intravenous electrolyte solutions and a group of commonly used therapeutic agents. Visual, spectrophotometric and microbiological assay techniques are to be used to establish the compatibility profiles of these admixtures.
","abstract_html":"<p>Through the years, various studies (1-5) have been done regarding the prevalent practice of adding one or more drugs to parenteral fluids. The greater variety of drugs being used intravenously, plus the formulation of newer and more complex parenteral fluids, has led to an increased awareness of potential incompatibilities existing between drug and solution. Recognition of the hazards of such extemporaneous combinations has necessitated the study of drug stability in solution.</p><p>The objective of this report is to determine compatibility characteristics of admixtures prepared from a series of balance intravenous electrolyte solutions and a group of commonly used therapeutic agents. Visual, spectrophotometric and microbiological assay techniques are to be used to establish the compatibility profiles of these admixtures.</p>","abstract_has_math":false,"creators":["Tozlian, Harry Michael"],"institution":null,"degree_name":"Master of Science (M.S.)","degree_level":"Thesis","degree_discipline":"Graduate School","degree_department":null,"school":null,"contributors":["James C. King"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":1975,"date_issued":"1975-01-01T08:00:00Z","date_published":"1975-01-01T08:00:00Z","updated_at":"2026-07-24T05:36:21Z","subjects":["Incompatibles (Pharmacy)","Drug interactions","Electrolyte solutions","Parenteral therapy","Medicine and Health Sciences"],"languages":[],"rights":[],"rights_urls":["http://rightsstatements.org/vocab/NKC/1.0/"],"identifier_entries":[]},"links":{"outbound_url":"https://scholarlycommons.pacific.edu/uop_etds/432","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["James C. King"]},{"key":"dc:creator","label":"Author","values":["Tozlian, Harry Michael"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.available","label":"Dc Date Available","values":["1975-01-01T08:00:00Z"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Graduate School"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Master of Science (M.S.)"]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Incompatibles (Pharmacy)","Drug interactions","Electrolyte solutions","Parenteral therapy","Medicine and Health Sciences"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["http://rightsstatements.org/vocab/NKC/1.0/"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarlycommons.pacific.edu/uop_etds/432"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Through the years, various studies (1-5) have been done regarding the prevalent practice of adding one or more drugs to parenteral fluids. The greater variety of drugs being used intravenously, plus the formulation of newer and more complex parenteral fluids, has led to an increased awareness of potential incompatibilities existing between drug and solution. Recognition of the hazards of such extemporaneous combinations has necessitated the study of drug stability in solution.
The objective of this report is to determine compatibility characteristics of admixtures prepared from a series of balance intravenous electrolyte solutions and a group of commonly used therapeutic agents. Visual, spectrophotometric and microbiological assay techniques are to be used to establish the compatibility profiles of these admixtures.
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The objective of this report is to determine compatibility characteristics of admixtures prepared from a series of balance intravenous electrolyte solutions and a group of commonly used therapeutic agents. Visual, spectrophotometric and microbiological assay techniques are to be used to establish the compatibility profiles of these admixtures.
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