{"id":{"repo_id":"texas","oai_identifier":"oai:repositories.lib.utexas.edu:2152/1542"},"canonical_url":"https://search.dev.ndltd.org/etd/texas/oai:repositories.lib.utexas.edu:2152/1542","repository":{"repo_id":"texas","name":"University of Texas","base_url":"https://repositories.lib.utexas.edu/server/oai/request"},"display":{"title":"Anions in hydrophobic environments: liquid-liquid extraction of sulfate and chloride, and membrane transport of chloride","abstract":"The transport of an anion across a lipid bilayer or the extraction of an anion into organic solution requires the stabilization of a charged species in a hydrophobic environment. Due to the similar energetic barriers of both processes, liquid-liquid extraction can potentially be used as a model for membrane transport. Carrier species that can efficiently extract anions from aqueous solutions into solvents such as chloroform, can potentially be utilized to facilitate the diffusion of those anions across a lipid bilayer or cell membrane. The research presented here explores the relationship between liquid-liquid extraction and membrane transport behavior. Chapter 1 presents an introduction to the equilibria reactions that are involved in extraction, the structure of lipid bilayers and a description of liposome models of cell membranes. Chapter 2 details the partitioning analysis of sulfate using radiotracers. Chapter 3 explores the chloride extraction behavior of several pyrrole-based molecules using radiotracer analysis. Chapter 4 details the extensive studies of chloride transport across lipid bilayers using liposome model membranes.","abstract_html":"The transport of an anion across a lipid bilayer or the extraction of an anion into organic solution requires the stabilization of a charged species in a hydrophobic environment. Due to the similar energetic barriers of both processes, liquid-liquid extraction can potentially be used as a model for membrane transport. Carrier species that can efficiently extract anions from aqueous solutions into solvents such as chloroform, can potentially be utilized to facilitate the diffusion of those anions across a lipid bilayer or cell membrane. The research presented here explores the relationship between liquid-liquid extraction and membrane transport behavior. Chapter 1 presents an introduction to the equilibria reactions that are involved in extraction, the structure of lipid bilayers and a description of liposome models of cell membranes. Chapter 2 details the partitioning analysis of sulfate using radiotracers. Chapter 3 explores the chloride extraction behavior of several pyrrole-based molecules using radiotracer analysis. Chapter 4 details the extensive studies of chloride transport across lipid bilayers using liposome model membranes.","abstract_has_math":false,"creators":["Eller, Leah Renee"],"institution":"The University of Texas at Austin","degree_name":"Doctor of Philosophy","degree_level":"Doctoral","degree_discipline":"Chemistry","degree_department":null,"school":null,"contributors":[],"advisors":["Sessler, Jonathan L."],"committee_chairs":[],"committee_members":[],"year":2005,"date_issued":"2005","date_published":"2005","updated_at":"2026-07-24T05:01:06Z","subjects":[],"languages":["eng"],"rights":["Copyright is held by the author. Presentation of this material on the Libraries' web site by University Libraries, The University of Texas at Austin was made possible under a limited license grant from the author who has retained all copyrights in the works."],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier","label":"Identifier","values":["b59832630"],"render_values":[{"text":"b59832630","href":null,"code":true}]}]},"links":{"outbound_url":"http://hdl.handle.net/2152/1542","outbound_label":"Handle","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Sessler, Jonathan L."]},{"key":"dc:creator","label":"Author","values":["Eller, Leah Renee"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date.accessioned","label":"Dc Date Accessioned","values":["2008-08-28T22:05:42Z"]},{"key":"dc:date.available","label":"Dc Date Available","values":["2008-08-28T22:05:42Z"]},{"key":"dc:date.issued","label":"Date","values":["2005"]},{"key":"thesis:degree_discipline","label":"Discipline","values":["Chemistry"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Doctoral"]},{"key":"thesis:degree_name","label":"Degree Name","values":["Doctor of Philosophy"]},{"key":"thesis:institution_name","label":"Thesis Institution Name","values":["The University of Texas at Austin"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:language.iso","label":"Language (ISO)","values":["eng"]},{"key":"dc:rights","label":"Dc Rights","values":["Copyright is held by the author. 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Carrier species that can efficiently extract anions from aqueous solutions into solvents such as chloroform, can potentially be utilized to facilitate the diffusion of those anions across a lipid bilayer or cell membrane. The research presented here explores the relationship between liquid-liquid extraction and membrane transport behavior. Chapter 1 presents an introduction to the equilibria reactions that are involved in extraction, the structure of lipid bilayers and a description of liposome models of cell membranes. Chapter 2 details the partitioning analysis of sulfate using radiotracers. Chapter 3 explores the chloride extraction behavior of several pyrrole-based molecules using radiotracer analysis. Chapter 4 details the extensive studies of chloride transport across lipid bilayers using liposome model membranes."]},{"key":"dc:format.medium","label":"Dc Format Medium","values":["electronic"]},{"key":"dc:title","label":"Title","values":["Anions in hydrophobic environments: liquid-liquid extraction of sulfate and chloride, and membrane transport of chloride"]}]}],"canonical_facts":{"dc:contributor.advisor":["Sessler, Jonathan L."],"dc:creator":["Eller, Leah Renee"],"dc:date.accessioned":["2008-08-28T22:05:42Z"],"dc:date.available":["2008-08-28T22:05:42Z"],"dc:date.issued":["2005"],"dc:description":["text"],"dc:description.abstract":["The transport of an anion across a lipid bilayer or the extraction of an anion into organic solution requires the stabilization of a charged species in a hydrophobic environment. Due to the similar energetic barriers of both processes, liquid-liquid extraction can potentially be used as a model for membrane transport. Carrier species that can efficiently extract anions from aqueous solutions into solvents such as chloroform, can potentially be utilized to facilitate the diffusion of those anions across a lipid bilayer or cell membrane. The research presented here explores the relationship between liquid-liquid extraction and membrane transport behavior. Chapter 1 presents an introduction to the equilibria reactions that are involved in extraction, the structure of lipid bilayers and a description of liposome models of cell membranes. Chapter 2 details the partitioning analysis of sulfate using radiotracers. Chapter 3 explores the chloride extraction behavior of several pyrrole-based molecules using radiotracer analysis. Chapter 4 details the extensive studies of chloride transport across lipid bilayers using liposome model membranes."],"dc:format.medium":["electronic"],"dc:identifier":["b59832630"],"dc:identifier.uri":["http://hdl.handle.net/2152/1542"],"dc:language.iso":["eng"],"dc:rights":["Copyright is held by the author. Presentation of this material on the Libraries' web site by University Libraries, The University of Texas at Austin was made possible under a limited license grant from the author who has retained all copyrights in the works."],"dc:title":["Anions in hydrophobic environments: liquid-liquid extraction of sulfate and chloride, and membrane transport of chloride"],"thesis:degree_discipline":["Chemistry"],"thesis:degree_level":["Doctoral"],"thesis:degree_name":["Doctor of Philosophy"],"thesis:institution_name":["The University of Texas at Austin"]},"updated_at":"2026-07-24T05:01:06Z"}