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University of Tennessee Health Science Center

Nursing Perspectives and Opinions on Early or Delayed Sepsis Treatment: A Mixed Methods Approach

Abstract

dc:description.abstract

<p>Purpose. Each year at least 1.7 million adults in America develop sepsis. Sepsis can lead to life threatening organ dysfunction, severe hypotension, and death when severe sepsis or septic shock is involved. Sepsis is responsible for 50% of acute kidney injury (AKI), which is the most common form of organ dysfunction seen in critical care. Sepsis associated AKI results in loss of, or decreased renal function, is associated with adverse long-term outcomes, and carries a higher mortality rate than non-septic AKI, sepsis without AKI, or septic shock without AKI. Surviving sepsis guidelines suggests a 1-hour window from the time of sepsis diagnosis to initiating critical treatments. Nurses are vital in identifying early signs and symptoms of sepsis. Early sepsis treatment is essential to hinder preventable sepsis deaths. The purpose of this study was to gauge how critical care nurses who work in ED and ICU perceive factors that might affect early or delayed sepsis treatment. Methods. An exploratory sequential mixed methods approach was performed to describe the study findings. Qualitative data was collected and analyzed from 14 nurses, whereby themes were extracted and explained using a phenomenological method. Descriptive statistics were used to analyze the results of a self-completed survey for the quantitative portion of the study. Surveys were given out to and collected from 100 nurses. The quantitative data was utilized to strengthen the themes of the qualitative themes. Results. Themes from the quantitative study corroborated qualitative findings. Study participants ranked poor communication and coordination of care, knowledge deficit regarding appropriate management, and lab delays as the 1st, 2nd, and 3rd greatest cause of delays in sepsis treatment, respectively. Although self-knowledge of sepsis identification was high among participants, sepsis management was more difficult. Conclusion. Sepsis bundles assist nurses in facilitating early sepsis treatment. Edu- cation programs dedicated to ED and ICU nurses are needed. Yearly continuing education programs focusing on sepsis management should be implemented to keep nurses well informed on sepsis identification and management.</p>

Degree

thesis:*
Name thesis:degree_name
Doctor of Philosophy (PhD)
Level thesis:degree_level
Dissertation
Discipline thesis:degree_discipline
Nursing Science
Year dc:date.available
2022

Author and committee

dc:creator, dc:contributor.*
Author dc:creator
  • Harris, Pamela L.
Contributors dc:contributor
  • Ann K. Cashion, Ph.D.

Subjects

dc:subject × 10

Identifiers

dc:identifier.*
Repository record dc:identifier
https://dc.uthsc.edu/dissertations/613
OAI identifier oai:identifier
oai:dc.uthsc.edu:dissertations-1613

Chain of custody

source
Harvested from
University of Tennessee Health Science Center
Base URL
dc.uthsc.edu/do/oai/
Last updated
2026-07-24
Source record
OAI-PMH GetRecord
citation

Harris, Pamela L.. Nursing Perspectives and Opinions on Early or Delayed Sepsis Treatment: A Mixed Methods Approach. Dissertation thesis, 2022. https://dc.uthsc.edu/dissertations/613