ASSESSMENT OF PERI-IMPLANT BONE MICROARCHITECTURE IN D4 BONE: AN EX VIVO MICROCT ANALYSIS

Objective: This study aimed to evaluate the impact of different implant designs on primary stability, peak insertion torque (PIT), implant stability quotient (ISQ), and peri-implant bone microarchitecture in low-density bone (D4). The investigation focused on three Straumann implant systems: Bone Level Tapered (BLT), Bone Level X (BLX), and Tissue Level (TL). Materials and Methods: An ex vivo model utilizing porcine tibia bone was employed. A total of 33 osteotomies were performed and implants were placed following the manufacturer’s recommendations. PIT was measured using a precision digital torque meter, and ISQ was recorded with Osstell® Mentor. Micro-computed tomography (µCT) analysis was conducted to evaluate peri-implant bone volume (BV), total volume (TV), bone volume fraction (BV/TV), and surface characteristics. Data were analyzed using ANOVA and post-hoc comparisons with significance set at p < 0.05. Results: ISQ values showed no significant differences among the three implant groups (p = 0.801), indicating comparable initial stability. However, PIT was significantly higher in the BLX group (34.9 ± 14.5 Ncm) compared to BLT (23.0 ± 8.1 Ncm, p = 0.04) and TL (21.2 ± 8.6 Ncm, p = 0.01). µCT analysis revealed that BLT implants exhibited significantly higher BV and BV/TV across multiple regions of interest (ROI1–ROI4) compared to BLX and TL implants (p < 0.0001). The BLX group demonstrated increased peri-implant bone volume in the apical region (ROI3, ROI4), while BLT exhibited higher bone volume in the coronal and midsections (ROI1, ROI2). TL implants showed the lowest BV/TV percentages, suggesting less bone compression. Surface analysis confirmed greater peri-implant bone contact in BLT, with significantly larger total VOI and object surfaces (p < 0.0001). Conclusion: BLX implants demonstrated higher PIT, suggesting increased mechanical engagement, whereas BLT implants exhibited greater peri-implant bone volume and surface contact. TL implants exhibited less peri-implant bone compression, which may affect primary stability. These findings provide insight into the role of implant design in influencing primary stability and peri-implant bone adaptation, with implications for immediate implant placement strategies in low-density bone. Further research is required to assess the long-term clinical impact of these differences.

Grantor dc:publisher

Temple University. Libraries

Year dc:date.issued

2025

Author dc:creator

• Sabbah, David

Advisor dc:contributor.advisor

• Santana, Ronaldo

Committee members dc:contributor.committeemember

• Semeniuk, David
• Sanavi, Farshid

• Dentistry
• Bone microarchitecture
• Dental implant
• Implant designs
• Implant stability quotient
• Peak insertion torque
• Primary stability

Statement dc:rights

• IN COPYRIGHT- This Rights Statement can be used for an Item that is in copyright. Using this statement implies that the organization making this Item available has determined that the Item is in copyright and either is the rights-holder, has obtained permission from the rights-holder(s) to make their Work(s) available, or makes the Item available under an exception or limitation to copyright (including Fair Use) that entitles it to make the Item available.

Licence dc:rights.uri

• http://rightsstatements.org/vocab/InC/1.0/

Language dc:language.iso

eng

Repository record dc:identifier.uri

https://scholarshare.temple.edu/handle/20.500.12613/11212

OAI identifier oai:identifier

oai:scholarshare.temple.edu:20.500.12613/11212