{"id":{"repo_id":"strathclyde","oai_identifier":"oai:strathclyde:br86b356q"},"canonical_url":"https://search.dev.ndltd.org/etd/strathclyde/oai:strathclyde:br86b356q","repository":{"repo_id":"strathclyde","name":"University of Strathclyde","base_url":"https://stax.strath.ac.uk/catalog/oai"},"display":{"title":"Metal-free C-H functionalisation methods","abstract":"This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography.","abstract_html":"This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography.","abstract_has_math":false,"creators":["Kubczyk, Tomasz Miroslaw"],"institution":"University of Strathclyde","degree_name":"phd","degree_level":"doctoral-pg","degree_discipline":null,"degree_department":null,"school":null,"contributors":[],"advisors":["Tomkinson, Nick"],"committee_chairs":[],"committee_members":[],"year":2016,"date_issued":"2016","date_published":"2016","updated_at":"2026-07-24T04:42:40Z","subjects":[],"languages":[],"rights":[],"rights_urls":[],"identifier_entries":[{"key":"dc:identifier.doi","label":"DOI","values":["10.48730/vb2t-ym02"],"render_values":[{"text":"10.48730/vb2t-ym02","href":"https://doi.org/10.48730/vb2t-ym02","code":true}]},{"key":"dc:identifier","label":"Identifier","values":["T14443"],"render_values":[{"text":"T14443","href":null,"code":true}]},{"key":"dc:creator.authoridentifier","label":"Author Identifier","values":["201198237"],"render_values":[{"text":"201198237","href":null,"code":true}]}]},"links":{"outbound_url":"https://stax.strath.ac.uk/concern/theses/br86b356q","outbound_label":"Repository record","outbound_source":"dc:identifier.uri"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor.advisor","label":"Advisor","values":["Tomkinson, Nick"]},{"key":"dc:creator","label":"Author","values":["Kubczyk, Tomasz Miroslaw"]},{"key":"dc:creator.authoridentifier","label":"Author Identifier","values":["201198237"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"dc:date","label":"Dc Date","values":["2016"]},{"key":"dc:date.issued","label":"Date","values":["2016"]},{"key":"dc:publisher.department","label":"Dc Publisher Department","values":["Department of Pure and Applied Chemistry"]},{"key":"dc:publisher.institution","label":"Dc Publisher Institution","values":["University of Strathclyde"]},{"key":"dc:type.qualificationlevel","label":"Dc Type Qualificationlevel","values":["doctoral-pg"]},{"key":"dc:type.qualificationname","label":"Dc Type Qualificationname","values":["phd"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["T14443"]},{"key":"dc:identifier.doi","label":"DOI","values":["10.48730/vb2t-ym02"]},{"key":"dc:identifier.uri","label":"Identifier URI","values":["https://stax.strath.ac.uk/concern/theses/br86b356q"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description","label":"Description","values":["Previously held under moratorium from 1 December 2016 until 6 December 2021","This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography."]},{"key":"dc:description.abstract","label":"Abstract","values":["This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography."]},{"key":"dc:title","label":"Title","values":["Metal-free C-H functionalisation methods"]}]}],"canonical_facts":{"dc:contributor.advisor":["Tomkinson, Nick"],"dc:creator":["Kubczyk, Tomasz Miroslaw"],"dc:creator.authoridentifier":["201198237"],"dc:date":["2016"],"dc:date.issued":["2016"],"dc:description":["Previously held under moratorium from 1 December 2016 until 6 December 2021","This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography."],"dc:description.abstract":["This thesis describes the development of two metal-free C–H functionalisation methods which encompass oxidations of sp³- and sp²-hybridised C–H bonds.Chapter 1 provides a brief introduction to the rapidly growing area of C–H functionalisation and outlines selected metal-catalysed and metal-free C–H functionalisation methods. Chapter 2 describes the development of a novel metal-free C–H functionalisation method of alkanes, from concept, through initial investigations, optimisation and substrate scope to mechanistic studies. Chapter 3 gives a detailed account of the development and mechanistic investigations of peroxide-mediated C–H functionalisation method exclusive to aromatic C–H bonds. Chapter 4 presents the experimental data obtained in the process of developing the new methodologies described herein. Chapter 5 contains an appendix. Chapter 6 contains a bibliography."],"dc:identifier":["T14443"],"dc:identifier.doi":["10.48730/vb2t-ym02"],"dc:identifier.uri":["https://stax.strath.ac.uk/concern/theses/br86b356q"],"dc:publisher.department":["Department of Pure and Applied Chemistry"],"dc:publisher.institution":["University of Strathclyde"],"dc:title":["Metal-free C-H functionalisation methods"],"dc:type.qualificationlevel":["doctoral-pg"],"dc:type.qualificationname":["phd"]},"updated_at":"2026-07-24T04:42:40Z"}