Neuroblastoma is the most prevalent extracranial childhood solid tumor with several stages of disease. While many children have an aggressive metastatic form of the disease, spontaneous regression has also been well documented. Individualized treatments are required due to the spectrum of disease staging, with MTD not necessary for many patients. Herein I propose several theoretical experiments that I believe will elucidate potential therapeutic treatment options. New dosages and combinations of drugs may be the key in preventing the relapse of NB.
","abstract_html":"<p>Neuroblastoma is the most prevalent extracranial childhood solid tumor with several stages of disease. While many children have an aggressive metastatic form of the disease, spontaneous regression has also been well documented. Individualized treatments are required due to the spectrum of disease staging, with MTD not necessary for many patients. Herein I propose several theoretical experiments that I believe will elucidate potential therapeutic treatment options. New dosages and combinations of drugs may be the key in preventing the relapse of NB.</p>","abstract_has_math":false,"creators":["Davis, Ashley Elizabeth"],"institution":null,"degree_name":"M.S.","degree_level":"Campus Access Thesis","degree_discipline":"Biomedical Science","degree_department":null,"school":null,"contributors":["Ugra Singh","Shekhar Patel"],"advisors":[],"committee_chairs":[],"committee_members":[],"year":2012,"date_issued":"2012-01-01T08:00:00Z","date_published":"2012-01-01T08:00:00Z","updated_at":"2026-07-24T04:38:31Z","subjects":["Biomedical","Chemicals and Drugs","Medicine and Health Sciences","Childhood Cancer","Docosahexaenoic acid (DHA)","Neuroblastoma","Resveratrol (RV)","Sparstolonin B (SsnB)"],"languages":[],"rights":["© 2012, Ashley Elizabeth Davis"],"rights_urls":[],"identifier_entries":[]},"links":{"outbound_url":"https://scholarcommons.sc.edu/etd/2097","outbound_label":"Repository record","outbound_source":"dc:identifier"},"metadata_groups":[{"id":"people","label":"People","entries":[{"key":"dc:contributor","label":"Contributor","values":["Ugra Singh","Shekhar Patel"]},{"key":"dc:creator","label":"Author","values":["Davis, Ashley Elizabeth"]}]},{"id":"academic_context","label":"Academic Context","entries":[{"key":"thesis:degree_discipline","label":"Discipline","values":["Biomedical Science"]},{"key":"thesis:degree_level","label":"Degree Level","values":["Campus Access Thesis"]},{"key":"thesis:degree_name","label":"Degree Name","values":["M.S."]}]},{"id":"subjects_keywords","label":"Subjects and Keywords","entries":[{"key":"dc:subject","label":"Dc Subject","values":["Biomedical","Chemicals and Drugs","Medicine and Health Sciences","Childhood Cancer","Docosahexaenoic acid (DHA)","Neuroblastoma","Resveratrol (RV)","Sparstolonin B (SsnB)"]}]},{"id":"language_rights","label":"Language and Rights","entries":[{"key":"dc:rights","label":"Dc Rights","values":["© 2012, Ashley Elizabeth Davis"]}]},{"id":"identifiers","label":"Identifiers","entries":[{"key":"dc:identifier","label":"Identifier","values":["https://scholarcommons.sc.edu/etd/2097"]}]},{"id":"additional","label":"Additional Metadata","entries":[{"key":"dc:description.abstract","label":"Abstract","values":["Neuroblastoma is the most prevalent extracranial childhood solid tumor with several stages of disease. While many children have an aggressive metastatic form of the disease, spontaneous regression has also been well documented. Individualized treatments are required due to the spectrum of disease staging, with MTD not necessary for many patients. Herein I propose several theoretical experiments that I believe will elucidate potential therapeutic treatment options. New dosages and combinations of drugs may be the key in preventing the relapse of NB.
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